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The type 1 σ receptor (σR1) has been shown to participate in a variety of functions in the central nervous system. To identify the specific regions of the brain that are involved in σR1 function, we analyzed the expression pattern of the receptor mRNA in the mouse brain by in situ hybridization. σR1 mRNA was detectable primarily in the cerebral cortex, hippocampus, and Purkinje cells of cerebellum...
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