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The pathological or physiological changes of the crystalline lens directly affect the eye accommodation and transmittance, and then increase the risk of the presbyopia and cataract for people in middle and old age groups. There is no universally accepted quantitative method to measure the lens' mechanical properties in vivo so far. This study aims to investigate the possibility of assessing the age-related...
The pathological or physiological changes of the crystalline lens directly affect the eye accommodation and transmittance, and then increase the risk of the presbyopia and cataract for people in middle and old age groups. This risk has a remarkable rise with age, seriously influencing the living quality of the elderly, and also posing a huge burden on public health. There is no universally accepted...
Non-alcoholic fatty liver disease (NAFLD) is a major health concern due to the increasing obesity epidemic and it has the risk to progress to liver fibrosis, cirrhosis and hepatocellular carcinoma. It is important to assess the severity of hepatic fibrosis for the risk-stratified management of patients with NAFLD. Ultrasound elastography is a new technique for evaluation of liver fibrosis and it has...
Hepatic steatosis is an important histologic factor in non-alcoholic fatty liver disease (NAFLD) spectrum. The aim of this study is to evaluate the impact of steatosis on liver fibrosis stiffness measurement by acoustic radiation force impulse (ARFI) elastography. Meanwhile, the dynamical mechanical analysis (DMA) test is performed to quantify the mechanical behavior of rat livers. The rat models...
Most of the ultrasound elasticity imaging techniques can't improve the resolution and penetration at the same time. Coded excitation has displayed the capability to improve the penetration by transmitting coded waves and decoding the RF echoes. But the effectiveness of this technique in ultrasound elastographic imaging methods has not been fully demonstrated. This paper introduces a phase modulation...
Most ultrasound elastographic methods utilize a purely elastic model to describe the liver mechanical properties. However, to describe tissue that is dispersive and to obtain an accurate measure of tissue elasticity, the tissue viscoelastic property should be examined. The objective of this study was to investigate the shear viscoelastic characteristics, as measured by ultrasound elastography, of...
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