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AimsMicro‐vesicles (MVs) from bone mesenchymal stem cells (MSCs) have been shown to contribute to the recovery of damaged kidney. The aims of the present study are to investigate the biological effects and repair mechanisms of MVs.
MethodsMicro‐vesicles were obtained from MSC supernatants. In vitro, the proximal tubular epithelial cells (HK‐2) were treated with transforming growth factor (TGF‐β1)...
Aims: Several studies have demonstrated administration of mesenchymal stem cells (MSC) could reverse kidney injury by paracrine mechanisms rather than by MSC transdifferentiation. Recently, a few researchers found microvesicles (MV) derived from MSC might be a paracrine mechanism for cell‐to‐cell communication. The aim of this study was to investigate the repair effects of MV in a 5/6 subtotal nephrectomy...
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