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Background Consumption of diet high in soy products is suggested to contribute to lower prostate cancer incidence in Asian men. But little has been known about the influences of dietary patterns on gut microbiota and microbiota-mediated isoflavone metabolism. Here, we determined the influences of western pattern diet on prostate carcinogenesis, gut microbiota and microbiota-mediated equol metabolism...
Background
High fat diet (HFD) and its responsive change of gut microbiota are associated with numerous diseases in human and animal studies. But how maternal and post‐weaning HFD may influence the tumorigenesis of prostate cancer (PCa) in male offspring has not yet been reported.
Methods
We studied both solitary and combined effects of maternal or/and post‐weaning HFD on the tumorigenesis of prostate...
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