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The vertebrate Zfhx1 transcription factor family comprises δEF1 and Sip1, which bind to CACCT‐containing sequences and act as transcriptional repressors. It has been a longstanding question whether these transcription factors share the same regulatory functions in vivo. It has been shown that neural crest (NC) delamination depends on the Sip1 activity at the cranial level in mouse and chicken embryos,...
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