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Citrus pectin (CP), a polysaccharide composed of [→4)-α-d-GalpA-(1→] n , was submitted to one or four carboxy-reduction cycles, resulting in CP-CR 1 and CP-CR 4 , which had 40% and 2% of GalpA units, respectively. The polysaccharides were chemically sulfated and their anticoagulant and antithrombotic effects determined. Sulfated polysaccharides (CP-S, CP-CR 1 S and...
A mannogalactan from Pleurotus ostreatoroseus (MgPr) was chemically sulfated to give MgPr-S1, which was evaluated for its anticoagulant and antithrombotic activities, bleeding tendency, and platelet aggregation.MgPr-S1 was partially characterized by HPSEC-MALLS, methylation analysis, and 13 C NMR spectroscopy. Its anticoagulant activity was determined by assays of aPTT, TT, α-thrombin and...
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