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Study Type – Aetiology (case control) Level of Evidence 2b
OBJECTIVETo evaluate the expression of nitric oxide synthase (NOS) isoforms after various reconstruction techniques in rats, to improve the understanding of neuronal repair mechanisms after radical prostatectomy, as Schwann cell‐seeded guidance tubes have been shown to promote cavernous nerve regeneration, and glial cell‐line‐derived neurotrophic...
Schwann cell–seeded guidance tubes have been shown to promote cavernous nerve regeneration, and the local delivery of neurotrophic factors may additionally enhance nerve regenerative capacity. The present study evaluates whether the transplantation of GDNF-overexpressing Schwann cells may enhance regeneration of bilaterally transected erectile nerves in rats.Silicon tubes seeded with either GDNF-overexpressing...
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