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Contrast agents for ultrasound imaging, composed of tiny gas microbubbles, have become a reality in clinical routine. They are extensively used in radiology for detection and characterization of various tumors and in cardiology for left ventricular opacification. Recent experimental studies showed that ultrasound waves in combination with contrast agent microbubbles increase transiently cell membrane...
Recent studies have shown that microbubbles under ultrasound (US) activation permeabilize plasma membrane. But the mechanism of permeabilization is not completely understood. The recurrent hypothesis assumes the formation of pores in the cell membrane allowing molecule delivery into cells. The aim of our study is to comfort this assumption by investigating whether US and microbubbles facilitate outward...
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