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The effect of diet composition on the uptake ofparticulates across the gastrointestinal epithelium hasbeen examined in fasted male weanling Sprague-Dawleyrats by estimating the systemic uptake of orally administered 2-μm latex polystyrenemicrospheres. Using a tissue solubilization assay,particle transfer in animals maintained on a fluid dietwas determined. A larger number of particles wastransferred...
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