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Epithin, a mouse type II transmembrane serine protease, is processed at Gly 149 and released from the membrane. Here, we report the identification of an epithin isoform, epithin(Δ), containing a 66 amino acid deletion from the full-length epithin, which is missing the 4th LDLRA domain and the protease activation sequence. This truncated isoform showed the same characteristic N-terminal processing...
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