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HLA-B27 positivity strongly influences Ankylosing spondylitis (AS) disease susceptibility and phenotype. The aim of this study was to analyse an AS cohort with respect to quality of life (ASQoL), extra-articular disease, markers of disease activity (BASDAI), functional capacity (BASFI), biologic requirement, and the influence of HLA-B27 on these parameters.Data recorded in 82 patients included demographics...
La prédisposition génétique à la spondylarthrite ankylosante (SPA) qui est liée à la présence de HLA-B27 est forte et concerne aussi son phénotype. Le but de cette étude a été d'analyser l'influence de HLA-B27 sur les caractéristiques d'une cohorte de patients atteints de SPA concernant la qualité de vie (ASQoL), les manifestations extra-articulaires, l'activité de la maladie (BASAI), les capacités...
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