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Encouraged by the anti‐inflammatory activity of hinokinin in vivo, which is also observed for the analogues dinitrohinokinin and diidrocubebin, herein we used in vitro and in silico methods to assess their selectivity profiles and predict their binding modes with Cyclooxygenases (COX‐1 and 2). The in vitro assays demonstrated dinitrohinokinin is about 13 times more selective for COX‐2 than for COX‐1,...
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