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A multifunctional drug delivery system is developed comprising biodegradable porous silicon microparticles that act as motherships to ferry different types of imaging and therapeutic nanoparticles loaded within their porous structure. An E‐selectin thioaptamer ligand is used to actively target this delivery system to the bone marrow vasculature where the payload is released as the porous silicon underwent...
The application of a multistage drug‐delivery system comprising biodegradable nanoporous silicon particles that allow for a site‐specific delivery of different imaging or therapeutic nanoparticles is presented by Mauro Ferrari and co‐workers on page H278. The image shows a silicon particle that releases a therapeutic payload into bone marrow tissue.
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