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Background
We previously demonstrated that adenosine monophosphate‐activated protein kinase (AMPKα) activity is significantly inhibited by Ser‐486/491 phosphorylation in cell culture and in vivo models of metastatic and castration‐resistant prostate cancer, and hypothesized these findings may translate to clinical specimens.
Methods
In this retrospective, single‐institution pilot study, 45 metastatic...
Objectives
To evaluate partial nephrectomy (PN) use in patients at higher risk for clinical progression, using a large national database of American patients.
Patients and Methods
We performed a retrospective review of patients with cN0/cM0 renal cell carcinoma from 2003 to 2011 using the National Cancer Data Base. Our primary endpoint was PN use for high‐risk disease, defined as ≥1 adverse pathological...
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