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Three neolignan glycosides, including a new compound (7S,8R)‐dihydro‐3′‐hydroxy‐7‐(4‐hydroxy‐3‐methoxyphenyl)‐1′‐benzofuranpropanol‐9‐O‐β‐D‐xylopyranoside (1), were isolated from the root of Nothopanax davidii. Their structures were determined by extensive spectroscopic analyses, particularly NMR, HR‐ESI‐MS, and ECD experiments, and the absolute configuration of 2 was first definitively determined...
Piper longum is a well‐known spice and traditional medicine. It was revealed to possess anti‐diabetic activity, but few information about its active component and underlying mechanism could be available. In this study, retrofractamides A (1) and C (2) isolated from P. longum showed potent inhibitory activity against PTP1B. Therefore, the potential mechanism was predicted by network pharmacology and...
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