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The BH3-only proapoptotic protein, BAD, was cloned from zebrafish embryos and its properties were characterized. Zebrafish BAD (zBAD) is a protein with 147 amino acids that contains a BH3 domain and a putative 14-3-3 binding site with the sequence of RPRSRS 84 AP, corresponding to S 136 in mouse BAD (mBAD). zBAD shares 34%, 28%, and 29% amino acid sequence identity to...
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