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Background InformationExosomes are small RNA‐ and protein‐containing extracellular vesicles (EVs) that are thought to mediate hetero‐ and homotypic intercellular communication between normal and malignant cells. Tumour‐derived exosomes are believed to promote re‐programming of the tumour‐associated stroma to favour tumour growth and metastasis. Currently, exosomes have been intensively studied in...
The employment of biomarkers (including imaging biomarkers, especially PET) in drug development has gained increasing attention during recent years. This has been partly stimulated by the hope that the integration of biomarkers into drug development programmes may be a means to increase the efficiency and effectiveness of the drug development process by early identification of promising drug candidates—thereby...
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