Search results for: Hideki Katagiri

Items from 1 to 20 out of 147 results

article

A newly identified compound activating UCP1 inhibits obesity and its related metabolic disorders

Ken Onodera, Yutaka Hasegawa, Nozomi Yokota, Shukuko Tamura, more

Obesity > 32 > 2 > 324 - 338

Objective Promoting thermogenesis in adipose tissue has been a promising strategy against obesity and related metabolic complications. We aimed to identify compounds that promote thermogenesis in adipocytes and to elucidate their functions and roles in metabolism. Methods To identify compounds that directly promote thermogenesis from a structurally diverse set of 4800 compounds, we utilized a cell‐based...

article

Continuous glucose monitoring in patients with remission of type 2 diabetes after laparoscopic sleeve gastrectomy without or with duodenojejunal bypass

Shojiro Sawada, Shinjiro Kodama, Satoko Tsuchiya, Satoko Kurosawa, more

Clinical Obesity > 10 > 6 > n/a - n/a

Bariatric surgery is associated with a high remission rate of type 2 diabetes mellitus. However, it is unclear whether patients showing remission of diabetes actually have normal blood glucose levels throughout the day. We therefore performed continuous glucose monitoring (CGM) in 15 ambulatory patients showing remission of diabetes after laparoscopic sleeve gastrectomy (LSG) without or with duodenojejunal...

article

Branched chain amino acids are associated with the heterogeneity of the area of lipid droplets in hepatocytes of patients with non‐alcoholic fatty liver disease

Eiji Kakazu, Akitoshi Sano, Tatsuki Morosawa, Jun Inoue, more

Hepatology Research > 49 > 8 > 860 - 871

Aim Macrovesicular steatosis around the central vein (zone 3) is one of the pathological features of non‐alcoholic fatty liver disease or steatohepatitis (NAFLD/NASH). The aim of this study is to elucidate precisely the association between the area of lipid droplets (LDs) and the plasma metabolic parameters in patients with NAFLD/NASH. Methods Eighty patients with NAFLD/NASH diagnosed by needle...

article

Diabetes care providers’ manual for disaster diabetes care

Jo Satoh, Koichi Yokono, Rie Ando, Toshinari Asakura, more

Diabetology International > 2019 > 10 > 3 > 153-179

To ensure that experiences and lessons learned from the unprecedented 2011 Great East Japan Earthquake are used to improve future disaster planning, the Japan Diabetes Society (JDS) launched the “Research and Survey Committee for Establishing Disaster Diabetes Care Systems Based on Relevant Findings from the Great East Japan Earthquake” under the supervision of the Chairman of the JDS. The Committee...

article

Enhancement of postprandial endogenous insulin secretion rather than exogenous insulin injection ameliorated insulin antibody-induced unstable diabetes: a case report

Keizo Kaneko, Chihiro Satake, Tomohito Izumi, Mamiko Tanaka, more

BMC Endocrine Disorders > 2019 > 19 > 1 > 1-7

Background Insulin injection, especially with insulin analogs, occasionally induces the production of insulin antibodies with high binding capacity and low affinity, similar to the insulin autoantibodies characteristic of insulin autoimmune syndrome (IAS). Production of these “IAS-like” insulin antibodies causes marked glycemic fluctuations with postprandial hyperglycemia and fasting hypoglycemia...

article

Glial Fatty Acid-Binding Protein 7 (FABP7) Regulates Neuronal Leptin Sensitivity in the Hypothalamic Arcuate Nucleus

Yuki Yasumoto, Hirofumi Miyazaki, Masaki Ogata, Yoshiteru Kagawa, more

Molecular Neurobiology > 2018 > 55 > 12 > 9016-9028

The hypothalamus is involved in the regulation of food intake and energy homeostasis. The arcuate nucleus (ARC) and median eminence (ME) are the primary hypothalamic sites that sense leptin and nutrients in the blood, thereby mediating food intake. Recently, studies demonstrating a role for non-neuronal cell types, including astrocytes and tanycytes, in these regulatory processes have begun to emerge...

article

Myriad mysteries of glucose homeostasis

Hideki Katagiri

Diabetology International > 2018 > 9 > 1 > 46-47

article

Activation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones

Yoichiro Asai, Tetsuya Yamada, Sohei Tsukita, Kei Takahashi, more

Gastroenterology > 2017 > 152 > 6 > 1521-1535.e8

Hypoxia-inducible factor 1α subunit (HIF1A) is a transcription factor that controls the cellular response to hypoxia and is activated in hepatocytes of patients with nonalcoholic fatty liver disease (NAFLD). NAFLD increases the risk for cholesterol gallstone disease by unclear mechanisms. We studied the relationship between HIF1A and gallstone formation associated with liver steatosis.We performed...

article

ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity

Toru Suzuki, Junhong Gao, Yasushi Ishigaki, Keiichi Kondo, more

Cell Reports > 2017 > 18 > 8 > 2045-2057

Obesity represents chronic inflammatory states promoted by pro-inflammatory M1-macrophage infiltration into white adipose tissue (WAT), thereby inducing insulin resistance. Herein, we demonstrate the importance of an ER stress protein, CHOP, in determining adipose tissue macrophage (ATM) polarity and systemic insulin sensitivity. A high-fat diet (HFD) enhances ER stress with CHOP upregulation in adipocytes...

article

MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic β-Cell Proliferation

Sohei Tsukita, Tetsuya Yamada, Kei Takahashi, Yuichiro Munakata, more

EBioMedicine > 2017 > 15 > Complete > 163-172

•BMT regenerates β-cells in mice with STZ-induced diabetes and increases miR-106b and miR-222 in serum exosomes and islets.•Inhibition with anti-miRs against these miRs suppresses BMT-induced β-cell regeneration.•Injection of miR-106b and miR-222 mimics promotes β-cell proliferation and improves hyperglycemia in STZ-treated mice.Regeneration of pancreatic β-cells is a promising therapeutic strategy...

article

Delayed graft duodenal perforation due to impacted food five years after simultaneous pancreas-kidney transplantation: A case report

Taizo Sakata, Hideki Katagiri, Tadao Kubota, Takashi Sakamoto, more

International Journal of Surgery Case Reports > 2017 > 38 > C > 69-72

Pancreas transplantation is the best treatment option in selected patients with type 1 diabetes mellitus. Here we report a patient with a nonmarginal duodenal perforation five years after a simultaneous pancreas-living donor kidney transplantation (SPLKT).A 31-year old male who underwent SPLKT five years previously presented with severe abdominal pain. He had a marginal duodenal perforation four years...

chapter

Introduction and Historical Remarks

Masatoshi Sakawa, Ichiro Nishizaki, Hideki Katagiri

International Series in Operations Research & Management Science > Fuzzy Stochastic Multiobjective Programming > 1-9

The main characteristics of the real-world decision making problems facing humans today are uncertain due to the increase in complexity of modern-day society as well as the diversification of values among people. Hence, when formulating a mathematical programming problem which closely describes and represents a real decision situation, various factors of the real system should be reflected in the...

chapter

Objective measurement for satisfaction values to sightseeing spots and route recommendation system

Takashi Hasuike, Hideki Katagiri, Hiroshi Tsuda

2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC) > 2699 - 2704

2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC)

This paper proposes a route recommendation system for sightseeing based on a network optimization problem. Sightseeing route planning is not difficult if a tourist initially sets satisfaction values of sightseeing spots numerically. However, it was hard to evaluate the satisfaction values objectively according to the tourist's feelings. The tourist can subjectively do a qualitative and pairwise comparison...

article

The relationship between advanced glycation end products and ocular circulation in type 2 diabetes

Kazuki Hashimoto, Hiroshi Kunikata, Masayuki Yasuda, Azusa Ito, more

Journal of Diabetes and its Complications > 2016 > 30 > 7 > 1371-1377

To determine whether skin autofluorescence (SAF) and serum pentosidine, biomarkers of advanced glycation end products (AGEs), were associated with ocular microcirculation in type 2 diabetes patients with early diabetic retinopathy (DR).This study included 46 eyes of 46 type 2 diabetes patients with no DR or non-proliferative DR. SAF was measured with an autofluorescence reader. Optic nerve head (ONH)...

chapter

A Subjective and Objective Constructing Approach for Reasonable Membership Function Based on Mathematical Programming

Takashi Hasuike, Hideki Katagiri

2016 Joint 8th International Conference on Soft Computing and Intelligent Systems (SCIS) and 17th International Symposium on Advanced Intelligent Systems (ISIS) > 59 - 64

2016 Joint 8th International Conference on Soft Computing and Intelligent Systems (SCIS) and 17th International Symposium on Advanced Intelligent Systems (ISIS)

This paper proposes a strict constructing approach for a reasonable membership function as objectively as possible. It is important to set a reasonable membership function to parameters for real-world decision making interactively and objectively. The main contribution of our proposed approach is to integrate a general continuous function derived from mathematical programming under a given probability...

article

A severe acute hypertriglyceridemic pancreatitis improved by plasma exchange treatment: A case report

Seiji Hongo, Kiyoshi Kume, Atushi Kanno, Naoki Yoshida, more

Pancreatology > 2016 > 16 > 4(S) > S136-S137

chapter

A Framework of Route Recommendation System for Sightseeing from Subjective and Objective Evaluation of Tourism Data

Takashi Hasuike, Hideki Katagiri, Hiroshi Tsuda

2016 5th IIAI International Congress on Advanced Applied Informatics (IIAI-AAI) > 801 - 806

2016 5th IIAI International Congress on Advanced Applied Informatics (IIAI-AAI)

This paper proposes a framework to recommend personal sightseeing route as well as to objectively obtain the tourist's utility to sightseeing plans and sightseeing spots from subjective comparison. The subjective comparison is qualitatively performed using a scale of measurement such as Likert scale, and the mathematical programming problem including this comparison as constraints is introduced. In...

article

Massive hematoma after fine-needle aspiration of the thyroid

Hideki Katagiri, Alan K. Lefor, Tadao Kubota, Ken Mizokami, more

Surgery > 2016 > 160 > 1 > 245-246

article

Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1‐Pparg pathway in adipogenesis

Mitsuyo Matsumoto, Keiichi Kondo, Takuma Shiraki, Andrey Brydun, more

Genes to Cells > 21 > 6 > 553 - 567

The transcription repressor BTB and CNC homology 1 (BACH1) represses genes involved in heme metabolism and oxidative stress response. BACH1 also suppresses the p53‐dependent cellar senescence in primary mouse embryonic fibroblasts (MEFs). To investigate the role of BACH1 in MEF other than its known functions, we carried out a genomewide mapping of binding site for BACH1 and its heterodimer partner...

chapter

An Agent-Based Simulation Model for Analysis on Marketing Strategy Considering Promotion Activities

Hideki Katagiri, Ichiro Nishizaki, Tomohiro Hayashida, Takahiro Daimaru

Lecture Notes in Computer Science > Agent and Multi-Agent Systems: Technologies and Applications > Agent-Based Simulation, Decision Making and Systems Optimization > 619-628

This paper proposes a new agent-based model for simulation analysis on firms’ marketing strategy in competitive markets environments. In the previous model proposed by Tay and Lasch, firm agents determine their marketing strategies such as price and product attribute at every period so as to maximize their profit. This paper shows that the firm agents constructed based on the Tay-Lasch model do not...

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INFONA - science communication portal

Search results for: Hideki Katagiri

A newly identified compound activating UCP1 inhibits obesity and its related metabolic disorders

Continuous glucose monitoring in patients with remission of type 2 diabetes after laparoscopic sleeve gastrectomy without or with duodenojejunal bypass

Branched chain amino acids are associated with the heterogeneity of the area of lipid droplets in hepatocytes of patients with non‐alcoholic fatty liver disease

Diabetes care providers’ manual for disaster diabetes care

Enhancement of postprandial endogenous insulin secretion rather than exogenous insulin injection ameliorated insulin antibody-induced unstable diabetes: a case report

Glial Fatty Acid-Binding Protein 7 (FABP7) Regulates Neuronal Leptin Sensitivity in the Hypothalamic Arcuate Nucleus

Myriad mysteries of glucose homeostasis

Activation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones

ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity

MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic β-Cell Proliferation

Delayed graft duodenal perforation due to impacted food five years after simultaneous pancreas-kidney transplantation: A case report

Introduction and Historical Remarks

Objective measurement for satisfaction values to sightseeing spots and route recommendation system

The relationship between advanced glycation end products and ocular circulation in type 2 diabetes

A Subjective and Objective Constructing Approach for Reasonable Membership Function Based on Mathematical Programming

A severe acute hypertriglyceridemic pancreatitis improved by plasma exchange treatment: A case report

A Framework of Route Recommendation System for Sightseeing from Subjective and Objective Evaluation of Tourism Data

Massive hematoma after fine-needle aspiration of the thyroid

Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1‐Pparg pathway in adipogenesis

An Agent-Based Simulation Model for Analysis on Marketing Strategy Considering Promotion Activities

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