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Purpose Non-functioning pituitary adenomas (NFPA) have a substantial impact on patients’ health status, yet research on the extent of healthcare utilization and costs among these patients is scarce. The objective was to determine healthcare usage, associated costs, and their determinants among patients treated for an NFPA. Methods In a cross-sectional study, 167 patients treated for an NFPA completed...
Introduction Pituitary tumors may have a considerable impact on patients’ functional status, including paid employment, yet research in this area is sparse. Objective To describe work disability and its determinants in patients treated for a pituitary tumor. Methods Cross-sectional study including patients treated for a pituitary tumor in the working age (18–65 years), who completed five validated...
Objective In rare disease research, most randomized prospective clinical trials can only use limited number of patients and are comprised of highly heterogeneous populations. Therefore, it is crucial to report the results in such a manner that it allows for comparison of treatment effectiveness and biochemical control between studies. The aim of this review was to investigate the current methods that...
After treatment for a non-functioning pituitary adenoma (NFA) health-related quality of life (HR-QoL) improves considerably. However, the literature about the normalization of HR-QoL after treatment is inconclusive. Some researchers described a persistently decreased HR-QoL compared to reference data, while others did not. Considering this variety in observed HR-QoL outcomes, the aim of the present...
Samenvatting Hypofyseapoplexie is een bloeding of infarct in de hypofyse en treedt meestal op in een hypofyseadenoom. De exacte pathofysiologie ervan is onbekend; wel wordt er een relatie met abnormale vasculatuur van een hypofyseadenoom beschreven. Het is een zeer zeldzame bijwerking van gonadoreline (GnRH)-agonisten. Wij beschrijven een 68-jarige man die een maand na toediening van gosereline, een...
Purpose Pituitary adenomas give rise to physical and psychological symptoms, which may persist after biochemical cure. Growing attention has been paid to quality of life (QoL) in these patients. We aimed to systematically analyze QoL assessment methods and QoL outcome in these patients. Methods We conducted a systematic literature search up to January 2014 in PubMed, Web of Knowledge, PsycInfo and...
To study the currently available data of recurrence rates of functioning and nonfunctioning pituitary adenomas following surgical cure and to analyze associated predisposing factors, which are not well established. A systematic literature search was conducted using Medline, Embase, Web of Science and the Cochran Library for studies reporting data on recurrence of pituitary adenoma after surgery, in...
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