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Pancreatic cancer is characterized by a high frequency of cachexia, pain and neural invasion (N‐inv). Neural damage is occurred by N‐inv and modulates pain and muscle atrophy via the activation of astrocyte in the connected spine. The activated astrocyte by N‐inv, thus, may affect cachexia in pancreatic cancer. Clinical studies in patients and autopsy cases with pancreatic cancer have revealed that...
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