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A defective switching off of the immune response is involved in several autoimmune diseases. This switching off involves Fas‐mediated apoptosis, perforin‐mediated fratricide of activated lymphocytes, and the suppressive activity of regulatory T (Treg) cells. These mechanisms are altered in autoimmune lymphoproliferative syndrome that often displays autoimmune thrombocytopenia. The aim of this research...
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