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To explore the effects of heme oxygenase-1 (HO-1) on vascular dysfunction in high fat diet streptozotocin-induced type 2 diabetic (T2D) rats.Rats received a high-fat diet followed by a low dose of streptozotocin (30mg/kg) to induce T2D. T2D rats were treated with hemin (1, 5, or 25mg/kg) or carbon monoxide-releasing molecule-2 (CORM-2, 5mg/kg) for 4weeks. Isometric contractions of aortic rings were...
To explore the effects of heme oxygenase-1 (HO-1) on vascular dysfunction in high fat diet streptozotocin-induced type 2 diabetic (T2D) rats.Rats received a high-fat diet followed by a low dose of streptozotocin (30mg/kg) to induce T2D. T2D rats were treated with hemin (1, 5, or 25mg/kg) or carbon monoxide-releasing molecule-2 (CORM-2, 5mg/kg) for 4weeks. Isometric contractions of aortic rings were...
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