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Background and PurposeTreatment with selective oestrogen receptor modulators (SERMs) reduces low‐density lipoprotein (LDL) cholesterol levels. We assessed the effect of tamoxifen, raloxifene and toremifene and their combinations with lovastatin on LDL receptor activity in lymphocytes from normolipidaemic and familial hypercholesterolaemic (FH) subjects, and human HepG2 hepatocytes and MOLT‐4 lymphoblasts...
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