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Background RNA molecules play many crucial roles in living systems. The spatial complexity that exists in RNA structures determines their cellular functions. Therefore, understanding RNA folding conformations, in particular, RNA secondary structures, is critical for elucidating biological functions. Existing literature has focused on RNA design as either an RNA structure prediction problem or an RNA...
This paper describes a three-phase approach to solving the bidline generation problem within airline flightcrew scheduling. Phase 1 builds “patterns” from existing pairings. Phase 2 builds bidlines from the “patterns” found in Phase 1 and solves a set partitioning problem to generate a final schedule. If Phase 2 fails to cover enough of the scheduled work, Phase 3 is used to fill in the uncovered...
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