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We have employed NMR techniques to probe the structure of several RNA fragments related to the loop I region of ColE1 RNA I. The secondary structure deduced from NMR spectra suggests that the loop I fragment consists of a stem of 11 base-pairs which contains a U-U base-pair and a bulged C base, a 7 nucleotide loop, and a single-stranded 5'end of 12 nucleotides. The UV-melting study of a 42-mer further...
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