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131I is used in treatment of metastatic thyroid cancer. Higher activity seems to improve the outcome compared to multiple lower treatments. Patient-specific dosimetry avoids adverse effects and allows appropriate metastasis irradiation. SPECT-TC is more accurate to estimate activity than planar methods.To define quantitative SPECT-TC lesion dosimetry protocol.Three hollow spheres (11.5, 5.6 and 1...
During the course of a radiotherapy treatment, volumes of interest might change and the doses delivered to patients may not match the planned dose any more. The delivered dose distributions can be directly estimated from the Cone Beam Computed Tomography (CBCT), images acquired at each session. For this purpose, it is first necessary to perform a registration between the computed tomography (CT) planning...
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