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Background and Aims
Intrahepatic cholangiocarcinoma (ICC) is aggressive and has high rates of relapse, conferring poor long‐term survival after curative resection. Little is known about the genomic evolution that occurs during ICC relapse.
Approach and Results
We conducted whole‐exome sequencing of 30 paired primary and relapsed tumors from 10 patients with ICC who received curative resection....
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