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Gut apical amino acid (AA) transport activity is high at birth and during suckling, thus being essential to maintain luminal nutrient-dependent mucosal growth through providing AA as essential metabolic fuel, substrates and nutrient stimuli for cellular growth. Because system-B0 Na+–neutral AA co-transporter (B0AT1, encoded by the SLC6A19 gene) plays a dominant role for apical uptake of large neutral...
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