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Fresh fruits are indispensable components in our daily diet. However, many fresh fruits are difficult to preserve for a long duration due to microbial contamination and maturity. Conventional fruit preservation techniques, such as cryopreservation, ozone, UV radiation and other physical and chemical methods, have drawbacks in terms of cost, potential hazards and residual toxic reagents. Therefore,...
Non-thermal atmospheric pressure plasma has been proved promising in many biomedical applications, such as decontamination, cancer inhibition and wound healing. However, the cell response mechanisms during these processes are far from clear. This is due to the complexity of both the plasma and biology system. Plasma has multi-dimensional parameters, and cells on the other hand can response in multiple...
Applications of atmospheric pressure cold plasma have been extended to various cancers therapy due to plasma-produced reactive oxygen species (ROS) inducing oxidative stress in cancer cell and consequently resulting in cell apoptosis. However, the mechanism of apoptosis caused by plasma is complicated. Actually, besides various kinds of intracellular ROS, calcium (Ca2t) also plays a critical role...
Recently, the study of plasma activated water (PAW) disinfection has attracted increasing researchers' attention. However, many questions of PAW disinfection still remain unanswered, especially for the mechanism of bacterial cell damage caused by PAW. More in-depth studies of the PAW disinfection are expected.
In previous studies, we have found that during atmospheric pressure cold plasma treatment, oxidative stress pathways are required for yeast cell response. In addition, overexpressions of anti-oxidant superoxide dismutase (SOD) genes can remarkably protective yeast cells from plasma injury. These results are in coincidence with other groups' findings with mammalian cells, thus encouraging us to explore...
Breast cancer is one of the major malignant tumors threatening the health of women. With the changes in people's lifestyle and diet, the incidence rate of breast cancer continues to rise all over the world. Despite the considerable progress in conventional cancer therapies such as surgery operation, radiotherapy, chemotherapy and incretion therapy, the intrinsic limitations of these therapies such...
Aesthetics of teeth, including tooth color, is of great importance to people. Conventional clinical tooth-whitening treatments are mainly based on hydrogen peroxide (H2O2), while some studies demonstrate that the bleaching process can be accelerated when enhanced by heat or light (laser, cold light). The dependence on H2O2 may lead to sensitivity or different degree of injury on soft tissue. As the...
Oral squamous cell carcinoma (OSCC) is the most widespread malignant oral cavity neoplasm, with even higher proportion of deaths than breast cancer and cervical cancer. Although advances were made in conventional treatment for OSCC such as surgery and radiation therapy, there has not been significant increase in the 5-year survival rate in the past four decades, and chemotherapeutic drug resistance...
In our previous studies, we have found that during atmospheric pressure cold plasma treatment, oxidative stress pathways are required for yeast cell response. In addition, overexpressions of anti-oxidant SOD genes can remarkably protective yeast cells from plasma injury. These results are in coincidence with other groups' findings with mammalian cells, thus encouraging us to explore more on the anti-oxidative...
Electron spin resonance (ESR) spectrometry is the most direct and sensitive method for detecting certain reactive oxygen species (ROS)1. By ESR diagnosis, plasma-water reactions can be elucidated, which is meaningful for guiding its clinical application.
A direct current atmospheric pressure cold plasma jet was used to inactivate Staphylococcus aureus (S. aureus) suspended in a liquid. Three types of gases, pure argon (99.999%), argon with 2% oxygen, and argon with 2% oxygen and 10% nitrogen were used as operating gases respectively. The inactivation efficacies for the plasma jets operating in the three gases decrease from Ar/O2(2%) to Ar/O2(2%)/N2(10%)...
Summary form only given. Dermatophytes are the most common aetiological agents, which invade into keratinized tissues (skin, hair, nails) of humans and animals causing dermatophytosis (also known as ringworm or tinea). Swimming pools, fitness centers, barber shops, beauty parlors, saunas and steam baths are common places to pick up superficial fungal infections. Mycotic infections have become more...
A cold plasma micro-jet (PMJ) has been shown very effective in inactivating numerous kinds of bacteria. However, when treating eukaryocytes, such as yeasts or human cells lines, the effects of a cold plasma on them are more complicated than simple inactivation. This may be due to the complex pathways within eukaryotic cells in response to different kind of stress. Here we used the budding yeast S...
A direct-current cold atmospheric-pressure air plasma microjet (PMJ) based on the microhollow cathode discharge design is used to inactivate six types of bacteria within a small well-defined area on a large Petri dish. We show that the PMJ is very effective in inactivating bacteria in their vegetative state as well as in the spore state within the area of plasma exposure. We also observed that bacteria...
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