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In this work, we have studied the different propagation patterns displayed in a human heart during acute ischemia. A 3-D geometrically and anatomically accurate regionally ischemic human heart was simulated. The ischemic region was located in the anterior side of the left ventricle mimicking the occlusion of the circumflex artery. Realistic heterogeneity and fiber anisotropy has been considered in...
Computer simulations have been used to study the mechanisms of postrepolarization refractoriness in cardiac cells under ischemic conditions at the cellular level. The ten Tusscher model of the cardiac action potential has been used with the formulation of the ATP-sensitive K+ current by Ferrero et al being adopted. Cells were subjected to hyperkalemia, hypoxic and acidic conditions. The results show...
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