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Despite the recent advancements in glycemic control for diabetic patients, the realization of an automated closed-loop artificial pancreas is still a challenge. The purpose of this research is to develop an integrated control system for in silico closed loop administration of insulin for Type 1 diabetic patients based on patients' medical record and real-time control-relevant data. The proposed system...
The greenhouse effect has brought about a series of ecological and environmental problems such as wind intensification, species extinction, acid rain, awful weather, sea-level rise, which are mainly caused by CO2 among all greenhouse gases. It is an effective way to alleviate the problem by injecting CO2 into shale reservoir. Such technology is the focus of attention of government and the public,...
This paper described the development and implementation of a distributed spectrum monitoring and surveillance testbed for identifying and locating RF signals using the Universal Software Radio Peripheral (USRP). We use a centralized RF trace collection testbed to establish the baseline, and we focus on distributed RF trace collection. Challenges associated with synchronization is identified and candidate...
Dezert-Smarandache Theory (DSmT) of plausible and paradoxical reasoning has excellent performance when the data contain uncertainty or conflicting. However, the methods developed in DSmT are in general very computationally expensive, thus they may not be directly applied to multiple data sources with high cardinality. In this paper, we explore the feasibility of using DSmT in practical applications...
In this study, the joint power control and scheduling problem in a multihop TD/CDMA MANET is investigated. A cluster based architecture is adopted to provide scalability and centralized control within clusters, and the corresponding power control and scheduling schemes are derived to maximize a network utility function and guarantee the minimum rate required by each traffic session. Because the resulted...
Because cancer usually involves multiple genes and pathways, combination therapy is considered as a promising approach for cancer treatment. However, when multiple drugs are taken by a patient simultaneously, toxicity becomes a concern. A potential solution is to give the drugs sequentially rather than simultaneously. In this study, we try to explore the feasibility of such an approach. Specifically,...
Awareness of our surrounding environment is very important. Traditional stationary air quality and pollution monitoring systems which installed in dedicated locations are usually bulky and expensive, and they may not be able to measure at locations of our interest. In this study, we propose a novel framework of an environment air quality monitoring system using a community-based approach. Leveraging...
In this work, we consider Quality of Service (QoS) guarantee for Device to Device (D2D) users co-existing with a cellular system where the D2D communication links are sharing radio spectrum resources with macrocell users in the downlink. Despite the lofty advantages associated with D2D communications, one major concern is the resulting interference from the D2D users, which should not infringe on...
This study takes advantage of the ability of Physical-Layer Network Coding (PNC) to embrace electromagnetic interference, improve spectral efficiency and achieve throughput optimality in a femtocell operated as a relay. Specifically, we make a case for a femtocell operating as a relay and utilizing PNC to eliminate the interference that exists between macrocells user equipments (MUEs) and femtocells...
The challenge of mitigating the Uplink (UL) interference in a two-tier heterogeneous network could be significantly improved by employing Physical-Layer Network coding (PNC) at a Home NodeB (HNB). This paper makes a case for a macrocell femtocell overlay network that utilizes PNC to mitigate the UL interference at the HNB. In closed subscriber group (CSG) UL information exchange, a Macrocell User...
In recent years, targeted therapy to treat cancer is gaining popularity. However, how to quantitatively and dynamically analyze the drug effect for molecularly targeted agents is quite different from traditional cytotoxic drugs. A novel preclinical model combining experimental methods and theoretical analysis is proposed to investigate the mechanisms of action and identify pharmacodynamic characteristic...
In this paper, a model that combining cell population and genetic regulation within a single cell by using stochastic hybrid systems is proposed. The objective is to study the response of a population of cancer cells to various drugs that targeting the proliferation and survival pathways. The proposed model captures both the dynamics of the cell population and the dynamics of gene regulations within...
The introduction of cognitive radio enables systems awareness of their environment and internal state, fulfills the need of dynamic spectrum access for higher spectrum utilization. However, at the same time, the use of cognitive radios further complicates the security problems in wireless networks and introduces additional challenges for a counter measure. Due to the intelligence of the attackers,...
Spectrum congestion refers to the situation where there are not enough frequencies to accommodate multiple radios or radio systems operating simultaneously. For instance, spectrum congestion is not uncommon in the unlicensed band, where multiple WiFi, Bluetooth, and Zigbee radios may compete for spectrum. Although there are many studies on spectrum congestion in the unlicensed band, it is not well...
A novel preclinical model combining experimental methods and theoretical analysis is proposed to investigate the mechanism of action and identify pharmacodynamic characteristic of a drug. Instead of fixed time point analysis of the drug exposure to drug effect, the time course of drug effect for different doses are quantitatively studied on cell line-based platforms using Kalman filter, where tumor...
In many mission-critical applications such as military operations or disaster relief efforts, wireless networks employing dynamic spectrum access enabled by cognitive radio technology gain popularity due to their high spectrum efficiency and interoperability. However, the use of cognitive radio further complicates the security problems in wireless networks and introduces additional challenges. For...
DST is now partly replaced by pumpout wireline formation tester in fluid sampling and reservoir productivity evaluation. With the successful development of the ERCT wireline tester in China, it is important to make advantage of the ERCT's large volume pumping capability, continuous testing property, complete sampling function and various fluid identity methods to evaluate reservoir more precisely...
Traditional material balance methods for calculating coal-bed methane reserves did not consider whether the coal seam was saturated or not; actually, they were only applicable for the saturated ones. Therefore, a material balance method applicable for unsaturated coal seams has been developed in this paper. In the derivation, the initial gas content is expressed as a Langmuir's equation with respect...
During the development of gas reservoir, gas wells would produce water. The sources of water can be divided into condensate water, working fluid and formation water. The accurate determination of the source of water can be conductive to determine the reasonable yield and prevent early water breakthrough. When the gas energy is insufficient, the gas can not fully carry the fluid out of wellhead. It...
In this paper, we propose to study the treatment and drug effects at the molecular level using a hybrid system model. Specifically, we propose a generic piecewise linear model to analyze drug effects on the state of the genes in a genetic regulatory network. We intend to answer the following question: given an initial state, would a treatment or drug (control input) drive the target gene to a new...
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