Search results for: Xiaoyan Tang

Items from 1 to 20 out of 186 results

article

A deep‐well plate enabled automated high‐throughput cell line development platform

Xiaoyan Tang, Jorge Quiroz, Yixiao Zhang, Jessica Pan, more

Biotechnology Progress > 40 > 3 > n/a - n/a

Cell line development (CLD) plays a crucial role in the manufacturing process development of therapeutic biologics. Most biologics are produced in Chinese hamster ovary (CHO) cell. Because of the nature of random transgene integration in CHO genome and CHO's inherent plasticity, stable CHO transfectants usually have a vast diversity in productivity, growth, and product quality. Thus, we often must...

article

Regulation by distinct MYB transcription factors defines the roles of OsCYP86A9 in anther development and root suberin deposition

Xiaoyan Huang, Yiqi Li, Zhenyi Chang, Wei Yan, more

The Plant Journal > 118 > 6 > 1972 - 1990

Cytochrome P450 proteins (CYPs) play critical roles in plant development and adaptation to fluctuating environments. Previous reports have shown that CYP86A proteins are involved in the biosynthesis of suberin and cutin in Arabidopsis. However, the functions of these proteins in rice remain obscure. In this study, a rice mutant with incomplete male sterility was identified. Cytological analyses revealed...

article

Achieving Exceptional Thermal and Hydrolytic Resistance in Chemically Circular Polyesters via In‐Chain 1,3‐Cyclobutane Rings

Chaoqun Weng, Zhiqiang Ding, Weijie Qiu, Bin Wang, more

Angewandte Chemie International Edition > 63 > 24 > n/a - n/a

Polyesters, a highly promising class of circular polymers for achieving a closed‐loop sustainable plastic economy, inherently exhibit material stability defects, especially in thermal and hydrolytic instability. Here, we introduce a class of polyesters, P(4^R‐BL) (R=Ph, Bu), featuring conformationally rigid 1,3‐cyclobutane rings in the backbone. These polyesters not only exhibit superior thermostability...

article

Achieving Exceptional Thermal and Hydrolytic Resistance in Chemically Circular Polyesters via In‐Chain 1,3‐Cyclobutane Rings

Chaoqun Weng, Zhiqiang Ding, Weijie Qiu, Bin Wang, more

Angewandte Chemie > 136 > 24 > n/a - n/a

article

QTL mapping of nitrogen use efficiency traits at the seedling and maturity stages under different nitrogen conditions in barley (Hordeum vulgare L.)

Zhaoyong Zeng, Shiyun Song, Jian Ma, Deyi Hu, more

Plant Breeding > 143 > 2 > 155 - 167

Nitrogen (N) is an essential element for plant growth and development. The identification and utilization of N use efficiency (NUE) loci are essential for breeding high NUE cultivars. In this study, 15 NUE traits were measured in a recombinant inbred line population containing 121 lines derived from the cross between a cultivated barley (Baudin) and a wild barley (CN4027). The hydroponic culture...

article

Tailoring the Properties of Polyhydroxyalkanoates from Plastics to Elastomers via Stereoselective Copolymerizations of rac‐β‐Butyrolactone and β‐Propiolactone

Haoran Zhang, Jiaojiao Qin, Xiaoyan Tang

Chinese Journal of Chemistry > 42 > 9 > 963 - 972

Poly(3‐hydroxybutyrate), a crucial member of the large biodegradable polyhydroxyalkanoate family, suffers from its brittleness. To enhance its performance, we employed a straightforward approach involving the ring‐opening copolymerization of racemic‐β‐butyrolactone (rac‐β‐BL) and β‐propiolactone (β‐PL) using the syndio‐selective amino‐alkoxy‐bis(phenolate)‐yttrium complex as a catalyst, thanks to...

article

The impact of long‐term antihypertensive treatment on wound healing after major non‐cardiac surgery in patients with cardiovascular diseases: A meta‐analysis

Yuwei Liu, Chunwei Ma, Xiaoyan Tang, Sha Liu, more

International Wound Journal > 21 > 4 > n/a - n/a

Hypertension is a prevalent condition that poses significant challenges in the perioperative management of patients undergoing major non‐cardiac surgery, particularly concerning wound healing and scar formation. This meta‐analysis assesses the impact of long‐term antihypertensive treatment on postoperative wound healing, examining data from seven studies involving patients who received such treatments...

article

Unraveling the complex pathophysiology of white matter hemorrhage in intracerebral stroke: A single‐cell RNA sequencing approach

Lisha Ye, Xiaoyan Tang, Jun Zhong, Wenfeng Li, more

CNS Neuroscience & Therapeutics > 30 > 3 > n/a - n/a

Aim This study aims to elucidate the cellular dynamics and pathophysiology of white matter hemorrhage (WMH) in intracerebral hemorrhage (ICH). Methods Using varying doses of collagenase IV, a consistent rat ICH model characterized by pronounced WMH was established. Verification was achieved through behavioral assays, hematoma volume, and histological evaluations. Single‐cell suspensions from the...

article

Ornithine δ‐aminotransferase OsOAT is critical for male fertility and cold tolerance during rice plant development

Wei Yan, Shuting Yuan, Yazhou Zu, Zhenyi Chang, more

The Plant Journal > 114 > 6 > 1301 - 1318

Cold stress is a major factor limiting the production and geographical distribution of rice (Oryza sativa) varieties. However, the molecular mechanisms underlying cold tolerance remain to be elucidated. Here, we report that ornithine δ‐aminotransferase (OsOAT) contributes to cold tolerance during the vegetative and reproductive development of rice. osoat mutant was identified as a temperature‐sensitive...

article

Circular Polymers from Ring‐Opening Polymerization of Five‐Membered (Thio)lactones and Derivatives

Chaoqun Weng, Xiaoyan Tang

Chinese Journal of Chemistry > 41 > 13 > 1603 - 1607

The short lifespan of most commercial plastics as disposables and the failure to adequately address the end‐of‐life issues of synthetic polymers have led to outrageous global plastic pollution and resource depletion. To solve the problem, one of the most effective strategies is to develop circular polymers and thus establish a new circular material economy. Polymers from ring‐opening polymerization...

article

Auxin participates in regulating the leaf curl development of Wucai (Brassica campestris L.)

Jinfeng Hou, Ying Xu, Shengnan Zhang, Xiaona Yang, more

Physiologia Plantarum > 175 > 2 > n/a - n/a

Wucai (Brassica campestris L. ssp. chinensis var. rosularis Tsen) belongs to the Brassica genus of the Cruciferae family, and its leaf curl is a typical feature that distinguishes Wucai from other nonheading cabbage subspecies. Our previous research found that plant hormones were involved in the development of the leaf curl in Wucai. However, the molecular mechanisms and the hormones regulating the...

article

Differential effects on natural killer cell production by membrane‐bound cytokine stimulations

Meiping Chang, Xiaoyan Tang, Luke Nelson, Gregg Nyberg, more

Biotechnology and Bioengineering > 119 > 7 > 1820 - 1838

Robust manufacturing production of natural killer (NK) cells has been challenging in allogeneic NK cell‐based therapy. Here, we compared the impact of cytokines on NK cell expansion by developing recombinant K562 feeder cell lines expressing membrane‐bound cytokines, mIL15, mIL21, and 41BBL, individually or in combination. We found that 41BBL played a dominant role in promoting up to 500,000‐fold...

article

Thrombus formation and ischemic necrosis of the uterus and adnexa due to purpura fulminans: A case report

Aki Maebayashi, Nobuki Hayashi, Saki Kamata, Atsunori Sugita, more

Journal of Obstetrics and Gynaecology Research > 47 > 12 > 4478 - 4483

Purpura fulminans (PF) is a syndrome characterized by the sudden onset of progressive skin hemorrhage, necrosis of the extremities, and thrombotic occlusion. Although the cause is believed to be protein C deficiency, many aspects of this syndrome have yet to be clarified. A 45‐year‐old Japanese woman, G2P2 (vaginal delivery), developed fever and lower abdominal pain. It was her 5th day of menstruation,...

article

Improvement of the efficiency and quality in developing a new CHO host cell line

Steven C. Huhn, Yang Ou, Xiaoyan Tang, Bo Jiang, more

Biotechnology Progress > 37 > 5 > n/a - n/a

Chinese hamster ovary (CHO) cells are a ubiquitous tool for industrial therapeutic recombinant protein production. However, consistently generating high‐producing clones remains a major challenge during the cell line development process. The glutamine synthetase (GS) and dihydrofolate reductase (DHFR) selection systems are commonly used CHO expression platforms based on controlling the balance of...

article

UCHL1 regulates inflammation via MAPK and NF‐κB pathways in LPS‐activated macrophages

Zhenhui Zhang, Ningning Liu, Xiaohua Chen, Fangcheng Zhang, more

Cell Biology International > 45 > 10 > 2107 - 2117

Inflammation is a common pathophysiological process as well as a clinical threat that occurs in various diseases worldwide. It is well‐documented that nuclear factor‐κB (NF‐κB) and mitogen‐activated protein kinase pathways are involved in inflammatory reactions to microbial infections in lipopolysaccharide (LPS)‐activated macrophages. The deubiquitinase ubiquitin carboxyl‐terminal hydrolase‐L1 (UCHL1)...

article

Enhancement of Transmission Efficiency on Pancharatnam−Berry Geometric Phase Encoding Metasurfaces

Xiaoyan Tang, Chenxia Li, Haiyong Gan, Yingwei He, more

Annalen der Physik > 533 > 2 > n/a - n/a

The modulation of the required light wavefront polarization and phase based on the geometric phase encoding metasurface (GPEM) has recently become a hot topic. However, the transmission coefficient of a geometric phase metasurface is greatly decreased when the structure is rotated. To address this problem, a solution of adding a tapered antireflection layer to the substrate and design an all‐dielectric...

article

Influence Mechanism of Barium Interface Layer on the Interfacial Properties of n‐Type 4H‐SiC Metal–Oxide–Semiconductor Capacitors

Zhiqiang Bai, Xiaoyan Tang, Yimeng Zhang, Yifan Jia, more

physica status solidi (b) > 257 > 12 > n/a - n/a

The 4H‐SiC/SiO₂ interface quality can be significantly improved by adding an alkaline earth metal interface layer. To study the passivation mechanism of the alkaline earth metal barium (Ba), a supercell model with a transition layer is established. As shown in the results from first‐principles calculations, the bandgap increases and the density of states decreases when SiBaO or OBaO structures...

article

The Fate of Lead (Pb) in Multitrophic Interactions Among Bacteria, Fungi, and Bacterivorous Soil Nematodes

Nadeem Iqbal, Saba Ahmed, Arshid Pervez, Rashid Nazir, more

CLEAN – Soil, Air, Water > 48 > 11 > n/a - n/a

Contamination of potentially toxic metals poses threats to living organisms due to prolonged existence in an ecosystem. The effects of toxic metals on soil microbes have broadly been reported but the study on interactions among soil micro‐ and macro‐organisms under metal stress needs to be elaborated. In current study, the immobilization of lead (Pb) is investigated by using five resistant microbial...

article

GDSL esterase/lipases OsGELP34 and OsGELP110/OsGELP115 are essential for rice pollen development

Huihui Zhang, Menglong Wang, Yiqi Li, Wei Yan, more

Journal of Integrative Plant Biology > 62 > 10 > 1574 - 1593

Pollen exine contains complex biopolymers of aliphatic lipids and phenolics. Abnormal development of pollen exine often leads to plant sterility. Molecular mechanisms regulating exine formation have been studied extensively but remain ambiguous. Here we report the analyses of three GDSL esterase/lipase protein genes, OsGELP34, OsGELP110, and OsGELP115, for rice exine formation. OsGELP34 was identified...

article

Identification of late‐stage pollen‐specific promoters for construction of pollen‐inactivation system in rice

Menglong Wang, Wei Yan, Xiaoqun Peng, Zhufeng Chen, more

Journal of Integrative Plant Biology > 62 > 8 > 1246 - 1263

Large‐scale production of male sterile seeds can be achieved by introducing a fertility‐restoration gene linked with a pollen‐killer gene into a recessive male sterile mutant. We attempted to construct this system in rice by using a late‐stage pollen‐specific (LSP) promoter driving the expression of maize α‐amylase gene ZM‐AA1. To obtain such promoters in rice, we conducted comparative RNA‐seq analysis...

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INFONA - science communication portal

Search results for: Xiaoyan Tang

A deep‐well plate enabled automated high‐throughput cell line development platform

Regulation by distinct MYB transcription factors defines the roles of OsCYP86A9 in anther development and root suberin deposition

Achieving Exceptional Thermal and Hydrolytic Resistance in Chemically Circular Polyesters via In‐Chain 1,3‐Cyclobutane Rings

Achieving Exceptional Thermal and Hydrolytic Resistance in Chemically Circular Polyesters via In‐Chain 1,3‐Cyclobutane Rings

QTL mapping of nitrogen use efficiency traits at the seedling and maturity stages under different nitrogen conditions in barley (Hordeum vulgare L.)

Tailoring the Properties of Polyhydroxyalkanoates from Plastics to Elastomers via Stereoselective Copolymerizations of rac‐β‐Butyrolactone and β‐Propiolactone

The impact of long‐term antihypertensive treatment on wound healing after major non‐cardiac surgery in patients with cardiovascular diseases: A meta‐analysis

Unraveling the complex pathophysiology of white matter hemorrhage in intracerebral stroke: A single‐cell RNA sequencing approach

Ornithine δ‐aminotransferase OsOAT is critical for male fertility and cold tolerance during rice plant development

Circular Polymers from Ring‐Opening Polymerization of Five‐Membered (Thio)lactones and Derivatives

Auxin participates in regulating the leaf curl development of Wucai (Brassica campestris L.)

Differential effects on natural killer cell production by membrane‐bound cytokine stimulations

Thrombus formation and ischemic necrosis of the uterus and adnexa due to purpura fulminans: A case report

Improvement of the efficiency and quality in developing a new CHO host cell line

UCHL1 regulates inflammation via MAPK and NF‐κB pathways in LPS‐activated macrophages

Enhancement of Transmission Efficiency on Pancharatnam−Berry Geometric Phase Encoding Metasurfaces

Influence Mechanism of Barium Interface Layer on the Interfacial Properties of n‐Type 4H‐SiC Metal–Oxide–Semiconductor Capacitors

The Fate of Lead (Pb) in Multitrophic Interactions Among Bacteria, Fungi, and Bacterivorous Soil Nematodes

GDSL esterase/lipases OsGELP34 and OsGELP110/OsGELP115 are essential for rice pollen development

Identification of late‐stage pollen‐specific promoters for construction of pollen‐inactivation system in rice

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