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In article number 2100006, Wen Sun, Wen‐fei Dong, Dan Shao, and co‐workers fabricate diselenide‐bridged mesoporous organosilica nanoparticles for coordination and redox dual‐responsive delivery of chemotherapeutic ruthenium compound KP1339. Such immunogenic cell death nano‐amplifier performed robust suppression on primary and distant tumor growth, as well as pulmonary metastasis of breast cancer with...
Amplifying the chemotherapy‐driven immunogenic cell death (ICD) for efficient and safe cancer chemoimmunotherapy remains a challenge. Here, a potential ICD nanoamplifier containing diselenide‐bridged mesoporous organosilica nanoparticles (MONs) and chemotherapeutic ruthenium compound (KP1339) to achieve cancer chemoimmunotherapy is tailored. KP1339‐loaded MONs show controlled drug release profiles...
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