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The pathogenesis of hepatitis C virus (HCV) infection is strongly influenced by the nature of the host's antiviral immunity. Counterintuitively, elevated serum concentrations of C‐X‐C chemokine 10 (CXCL10), a potent chemoattractant for antiviral T‐cells and NK‐cells, are associated with poor treatment outcomes in patients with chronic HCV. It has been reported that an N‐terminal truncated form of...
Viral hepatitis is the leading cause of liver disease worldwide and can be caused by several agents, including hepatitis A (HAV), B (HBV), and C (HCV) virus. We employed multiplexed protein immune assays to identify biomarker signatures of viral hepatitis in order to define unique and common responses for three different acute viral infections of the liver. We performed multianalyte profiling, measuring...
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