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Deer species (family Cervidae) are often part of the Mycobacterium tuberculosis complex maintenance host community, and tuberculosis (TB) control in deer, including vaccination, is consequently an area of ongoing research. However, most research into deer vaccination against TB is focused on using the live bacillus Calmette Guerin (BCG). Oral inactivated vaccines represent an interesting alternative...
The aim of this study was to assess whether genetic polymorphism of three important candidate cytokine genes, IL-10 (−1082G/A, −819C/T, and −592C/A), IL-4 (−590C/T) and TNF-α (−308G/A), play a role in the susceptibility to developing drug-induced liver injury (DILI), and in determining its phenotypic expression and severity.Cytokine genotyping was analysed using TaqMan 5′ allelic discrimination assay...
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