Wyniki wyszukiwania dla: Diana Blank

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artykuł

The Role of Attachment Style and Depression in Patients with Hepatitis C

Sanjeev Sockalingam, Diana Blank, Abdulqader Al Jarad, Fahad Alosaimi, więcej

Journal of Clinical Psychology in Medical Settings > 2013 > 20 > 2 > 227-233

Patients infected with chronic hepatitis C virus (HCV) commonly suffer from the triad of depression, pain and fatigue. This symptom triad in HCV is likely influenced by additional psychological and interpersonal factors, although the relationship is not clearly understood. This retrospective study aimed to characterize the relationship between attachment style and depressive and physical symptoms...

artykuł

Identifying opportunities to improve management of autoimmune hepatitis: Evaluation of drug adherence and psychosocial factors

Sanjeev Sockalingam, Diana Blank, Nour Abdelhamid, Susan E. Abbey, więcej

Journal of Hepatology > 2012 > 57 > 6 > 1299-1304

Recognizing the importance of adherence to therapy in autoimmune hepatitis (AIH) is critical for patient care and avoidance of unnecessary intervention. The influence of psychosocial factors on treatment adherence needs better understanding and prominence. We sought to determine the association between anxiety, depressive symptoms, and avoidant relationship style on self-reported immunosuppressant...

artykuł

A Comparison of Depression Screening Instruments in Hepatitis C and the Impact of Depression on Somatic Symptoms

Sanjeev Sockalingam, Diana Blank, Abdulqader Al Jarad, Fahad Alosaimi, więcej

Psychosomatics > 2011 > 52 > 5 > 433-440

Treatment of hepatitis C (HCV) with pegylated interferon-alpha (IFNα) can cause depression in approximately 30% of patients and underscores the need for effective detection of depression prior to and during IFNα treatment. Elevated rates of depression in untreated HCV can be a barrier to initiating HCV therapy and can impact fatigue and physical symptoms. In this preliminary study, we examined the...

artykuł

Treatment of co-morbid cocaine dependence in schizophrenia with topiramate

Katrina Lising-Enriquez, Diana Blank, Sandra J. Cushing, Ingrid C. Bacher, więcej

Schizophrenia Research > 2010 > 116 > 1 > 97

artykuł

Bipolar disorder and suicide: Research synthesis and clinical translation

Roger S. McIntyre, David J. Muzina, David E. Kemp, Diana Blank, więcej

Current Psychiatry Reports > 2008 > 10 > 1 > 66-72

Attempted suicide and suicide are prevalent in individuals with bipolar disorder (BD). Extant evidence indicates that history of suicide attempts, percentage of time spent in a depressed state, and hostility are factors associated with suicide attempts and completed suicide. Childhood adversity (eg, sexual and physical abuse) is emerging as a risk factor for suicide attempts in adults with BD. The...

artykuł

The anticancer prodrugs of butyric acid AN-7 and AN-9, possess antiangiogenic properties

Diana Blank-Porat, Tal Gruss-Fischer, Nataly Tarasenko, Zvi Malik, więcej

Cancer Letters > 2007 > 256 > 1 > 39-48

The antiangiogenic and antineoplastic activities of the butyric acid prodrugs AN-7 and AN-9 were demonstrated in vitro with HUVEC by inhibition of proliferation and vascular tubes formation, enhanced apoptosis, and inhibition of 22Rv-1 cells migration. In the sc implanted human prostate tumors (22Rv-1) in nude mice, AN-7 significantly inhibited Ki-67, HIF-1α, HER-2/neu, bFGF and increased PTEN level...

artykuł

A Role for SSU72 in Balancing RNA Polymerase II Transcription Elongation and Termination

Bernhard Dichtl, Diana Blank, Martin Ohnacker, Arno Friedlein, więcej

Molecular Cell > 2002 > 10 > 5 > 1139-1150

Interactions of pre-mRNA 3′end factors and the CTD of RNA polymerase II (RNAP II) are required for transcription termination and 3′end processing. Here, we demonstrate that Ssu72p is stably associated with yeast cleavage and polyadenylation factor CPF and provide evidence that it bridges the CPF subunits Pta1p and Ydh1p/Cft2p, the general transcription factor TFIIB, and RNAP II via Rpb2p. Analyses...

artykuł

Human Pre-mRNA Cleavage Factor I _m Is Related to Spliceosomal SR Proteins and Can Be Reconstituted In Vitro from Recombinant Subunits

Ursula Rüegsegger, Diana Blank, Walter Keller

Molecular Cell > 1998 > 1 > 2 > 243-253

Four polypeptides of 25, 59, 68, and 72 kDa copurify with the activity of human cleavage factor I _m (CF I _m ) involved in pre-mRNA 3' end processing. We report here the cloning of the 25 and 68 kDa subunits and the reconstitution of functional CF I _m ² ⁵ ^/ ⁶ ⁸ from these two polypeptides. Several lines of evidence indicate that CF I _m exists in at...

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Elsevier (6)
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Molecular Cell (2)
Cancer Letters (1)
Current Psychiatry Reports (1)
Journal of Clinical Psychology in Medical Settings (1)
Journal of Hepatology (1)
Psychosomatics (1)
Schizophrenia Research (1)

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