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BACKGROUNDMicroRNAs (miRNAs) are a class of short non‐coding RNAs that function in diverse biological processes. Aberrant miR‐152 expression has been frequently reported in various malignant tumors. However, the mechanism of miR‐152 in prostate cancer (PCa) remains unclear. This study aims to determine the function of miR‐152 in PCa cells and identify the novel molecular targets regulated by miR‐152...
BACKGROUNDApoptosis is the physiological mechanism of programmed cell death and abnormal regulation of this pathway can lead to carcinogenesis. We hypothesized that the FAS −1377G>A, −670A>G, and FASL −844T>C polymorphisms are associated with risk of prostate cancer (PCa).
MATERIALS AND METHODSWe genotyped polymorphisms in a hospital‐based case–control study of 602 patients diagnosed with...
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