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Objective
To investigate the involvement and role of receptor‐interacting protein 3 (RIP3)‐mediated necroptosis in periodontitis.
Methods
A periodontitis murine model was established by oral infection with Porphyromonas gingivalis, and activation of necroptosis pathway was identified by immunohistochemistry. Adeno‐associated virus was used to knock down Rip3 and the effect of Rip3 knockdown on...
Objective
To explore the mechanism of receptor‐interacting protein 1 (RIP1)‐mediated necroptosis during periodontitis progression.
Background
RIP3 and mixed lineage kinase domain‐like protein (MLKL) have been detected to be upregulated in periodontitis models. Because RIP1 is involved in necroptosis, it might also play a role in the progression of periodontitis.
Methods
An experimental periodontitis...