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Phenylpropanolamine (PPA)‐induced appetite control is associated with oxidative stress in the hypothalamus. This study explored whether hypothalamic antioxidants participated in hypothalamic ghrelin system‐associated appetite control in PPA‐treated rats. Rats were given PPA daily for 4 days, and changes in food intake and the expression of neuropeptide Y (NPY), the cocaine‐ and amphetamine‐regulated...
There has been a growing interest in applying pattern classification methods to discriminate patients with neurodegenerative diseases from normal controls using structural MRI data. Despite an impressive array of publications, most applications are framed as discrimination problems with categorical class decisions. For many clinical applications, probabilistic estimation would be more useful, especially...
In this paper, we present an effective computational approach for learning patterns of brain activity from the fMRI data. The procedure involved correcting motion artifacts, spatial smoothing, removing low frequency drifts and applying multivariate linear and non-linear kernel methods. Two novel techniques are applied: one utilizes the cosine transform to remove low-frequency drifts over time and...
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