Search results for: Piet Claus

Items from 1 to 20 out of 102 results

article

Use of Real‐Time Cine MRI to Assess the Respirophasic Variation of the Inferior Vena Cava—Proof‐of‐Concept and Validation Against Transthoracic Echocardiography

Jan Bogaert, Youri Bekhuis, Thomas Rosseel, Stijn Laveaux, more

Journal of Magnetic Resonance Imaging > 59 > 5 > 1809 - 1817

Background In clinical practice, the right heart filling status is assessed using the respirophasic variation of the inferior vena cava (IVC) assessed by transthoracic echocardiography (TTE) showing moderate correlations with the catheter‐based reference standard. Purpose To develop and validate a similar approach using MRI. Study Type Prospective. Population 37 male elite cyclists (mean age...

article

Use of 3D anatomical models in mock circulatory loops for cardiac medical device testing

Maria Rocchi, Marcus Ingram, Piet Claus, Jan D'hooge, more

Artificial Organs > 47 > 2 > 260 - 272

Introduction Mock circulatory loops (MCLs) are mechanical representations of the cardiovascular system largely used to test the hemodynamic performance of cardiovascular medical devices (MD). Thanks to 3 dimensional (3D) printing technologies, MCLs can nowadays also incorporate anatomical models so to offer enhanced testing capabilities. The aim of this review is to provide an overview on MCLs and...

article

Altered adrenergic response in myocytes bordering a chronic myocardial infarction underlies in vivo triggered activity and repolarization instability

Eef Dries, Matthew Amoni, Bert Vandenberk, Daniel M. Johnson, more

The Journal of Physiology > 598 > 14 > 2875 - 2895

Key points Ventricular arrhythmias are a major complication after myocardial infarction (MI), associated with sympathetic activation. The structurally heterogeneous peri‐infarct zone is a known substrate, but the functional role of the myocytes is less well known. Recordings of monophasic action potentials in vivo reveal that the peri‐infarct zone is a source of delayed afterdepolarizations (DADs)...

article

Area of the pressure-strain loop during ejection as non-invasive index of left ventricular performance: a population study

Nicholas Cauwenberghs, Mahdi Tabassian, Lutgarde Thijs, Wen-Yi Yang, more

Cardiovascular Ultrasound > 2019 > 17 > 1 > 1-11

Background Previous studies highlighted the usefulness of integrating left ventricular (LV) deformation (strain) and hemodynamic parameters to quantify LV performance. In a population sample, we investigated the anthropometric and clinical determinants of a novel non-invasive index of LV systolic performance derived from simultaneous registration of LV strain and brachial pressure waveforms. Methods...

article

Inter-vendor reproducibility and accuracy of segmental left ventricular strain measurements using CMR feature tracking

Monica Dobrovie, Manuel Barreiro-Pérez, Davide Curione, Rolf Symons, more

European Radiology > 2019 > 29 > 12 > 6846-6857

Objectives Our aim was to evaluate the inter-vendor reproducibility of cardiovascular MR feature tracking (CMR-FT) for the measurement of segmental strain (SS) of the left ventricle (LV) as well as to test the accuracy of CMR-FT to detect regional myocardial pathology. Methods We selected 45 patients: 15 with normal CMR findings, 15 with dilated cardiomyopathy, and 15 with acute myocardial infarction...

article

Left ventricular global myocardial strain assessment comparing the reproducibility of four commercially available CMR-feature tracking algorithms

Manuel Barreiro-Pérez, Davide Curione, Rolf Symons, Piet Claus, more

European Radiology > 2018 > 28 > 12 > 5137-5147

Objectives To compare the reproducibility of cardiovascular magnetic resonance feature-tracking (CMR-FT) packages to assess global left ventricular (LV) myocardial strain. Methods In 45 subjects (i.e. 15 controls, 15 acute myocardial infarction, 15 dilated cardiomyopathy patients), we determined inter-vendor, inter-observer (two readers) and intra-observer reproducibility of peak systolic global...

article

Low-flow support of the chronic pressure–overloaded right ventricle induces reversed remodeling

Tom Verbelen, Piet Claus, Daniel Burkhoff, Ronald B. Driesen, more

The Journal of Heart and Lung Transplantation > 2018 > 37 > 1 > 151-160

Mechanical right ventricular (RV) support in pulmonary arterial hypertension patients has been feared to cause pulmonary hemorrhage and to be detrimental for the after-load–sensitive RV. Continuous low-flow pumps offer promise but remain insufficiently tested.The pulmonary artery was banded in 20 sheep in this study. Eight weeks later, a Synergy micro-pump (HeartWare International, Framingham MA)...

article

Atrial volume and function during exercise in health and disease

Frédéric Schnell, Guido Claessen, André La Gerche, Piet Claus, more

Journal of Cardiovascular Magnetic Resonance > 2017 > 19 > 1 > 1-12

Background Although atrial function has prognostic significance in many cardiovascular conditions, changes during exercise have not previously been assessed. The aim of this study was to evaluate left atrial (LA) and right atrial (RA) volume and function during incremental exercise, both in normal individuals, healthy athletes, and in patients with chronic thromboembolic pulmonary hypertension (CTEPH)...

article

Left Ventricular Myocardial Segmentation in 3-D Ultrasound Recordings: Effect of Different Endocardial and Epicardial Coupling Strategies

Joao Pedrosa, Daniel Barbosa, Brecht Heyde, Frederic Schnell, more

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control > 2017 > 64 > 3 > 525 - 536

Cardiac volume/function assessment remains a critical step in daily cardiology, and 3-D ultrasound plays an increasingly important role. Though development of automatic endocardial segmentation methods has received much attention, the same cannot be said about epicardial segmentation, in spite of the importance of full myocardial segmentation. In this paper, different ways of coupling the endocardial...

article

Right ventricular and pulmonary vascular reserve in asymptomatic BMPR2 mutation carriers

Guido Claessen, Andre La Gerche, Thibault Petit, Hilde Gillijns, more

Journal of Heart and Lung Transplantation > 2017 > 36 > 2 > 148-156

Non-invasive estimates have suggested that asymptomatic BMPR2 mutation carriers may have an abnormal pulmonary vascular response to exercise and hypoxia. However, this has not been assessed with “gold standard” invasive measures.Eight controls and 8 asymptomatic BMPR2 mutation carriers underwent cardiac magnetic resonance imaging with simultaneous invasive pressure recording during bicycle exercise...

chapter

A Convolution-based Methodology to Simulate Cardiac Ultrasound Data Sets: Integration of Realistic Beam Profiles

Hang Gao, Piet Claus, G. Harry van Lenthe, Siegfried Jaecques, more

IFMBE Proceedings > 4th European Conference of the International Federation for Medical and Biological Engineering > Modeling and Simulation > 2520-2523

In ultrasound research, the simulation of ultrasound (US) images has become a standard tool. An easy and fast methodology that has been used extensively is the so-called convolution model in which the point spread function (PSF) of the imaging system is spatially (2D/3D) convolved with a Diractrain representing the position and reflectivity of discrete scattering sites. A new convolution-based methodology...

article

Accuracy of Echocardiography to Evaluate Pulmonary Vascular and RV Function During Exercise

Guido Claessen, Andre La Gerche, Jens-Uwe Voigt, Steven Dymarkowski, more

JACC: Cardiovascular Imaging > 2016 > 9 > 5 > 532-543

The authors have compared exercise echocardiography and exercise cardiac magnetic resonance imaging with simultaneous invasive pressure registration (ExCMR_ip) for the assessment of pulmonary vascular and right ventricular (RV) function.Exercise echocardiography may enable early diagnosis of pulmonary vascular disease, but its accuracy is untested.Exercise imaging was performed in 61 subjects (19 athletes,...

article

Evaluation of state-of-the-art segmentation algorithms for left ventricle infarct from late Gadolinium enhancement MR images

Rashed Karim, Pranav Bhagirath, Piet Claus, R. James Housden, more

Medical Image Analysis > 2016 > 30 > C > 95-107

Studies have demonstrated the feasibility of late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging for guiding the management of patients with sequelae to myocardial infarction, such as ventricular tachycardia and heart failure. Clinical implementation of these developments necessitates a reproducible and reliable segmentation of the infarcted regions. It is challenging...

chapter

Why Ischemic Hearts Respond Less to Cardiac Resynchronisation Therapy. A Modeling Study

Piet Claus, Bart Bijnens, Ole-Alexander Breithardt, George R. Sutherland

Lecture Notes in Computer Science > Functional Imaging and Modeling of the Heart > Session 6: Data Acquisition, Experimental, and Modeling Studies > 287-294

Cardiac Resynchronisation Therapy (CRT) by means of simultaneous biventricular or multisite leftventricular pacing is a new technique for improving left ventricular systolic performance in patients with heart failure and conduction abnormalities (e.g. left bundle branch block). However, different pathological cases do react differently to CRT and the underlying mechanisms are poorly understood. This...

chapter

Left-Ventricular Shape Determines Intramyocardial Stroke Work Distribution

Hon Fai Choi, Frank E. Rademakers, Piet Claus

Lecture Notes in Computer Science > Functional Imaging and Modeling of the Heart > Oral Session 5: Cardiac Mechanics, Cardiac Electrophysiology > 401-408

The left-ventricle often undergoes large shape changes in the remodelling process, which is now considered to be an important indication of disease progression. Therefore, the influence on intramyocardial work load distribution was examined in a finite-element study. Hereto, models were constructed with varying shapes, ranging from an elongated ellipsoid to a sphere, while the initial cavity and wall...

chapter

Post-Systolic Thickening in Ischaemic Myocardium: A Simple Mathematical Model for Simulating Regional Deformation

Piet Claus, Bart Bijnens, Frank Weidemann, Christoph Dommke, more

Lecture Notes in Computer Science > Functional Imaging and Modeling of the Heart > Towards Electromechanical Modeling > 134-139

We present a one-dimensional mathematical model to explain changes in regional radial myocardial deformation during ischaemia. The model makes use of cellular contraction properties of normal and ischaemic myocytes extracted from an animal model of induced chronic, regional ischaemia of the posterior wall. Simulations of the model are compared to the deformation patterns observed in the experimental...

chapter

Near horizon supergravity superspace

Piet Claus

Lecture Notes in Physics > Quantum Aspects of Gauge Theories, Supersymmetry and Unification > 375-381

We present a construction of the superspace of maximally supersymmetric adS _p+2×S ^d−p−2 near-horizon geometry based entirely on the supergravity constraints of which the bosonic space is a solution. Besides the geometric superfields, i.e. the vielbeine and the spinconnection, we also derive the isometries of the superspace together with the compensating...

chapter

The Relationship between Regional Integrated Backscatter Levels and Regional Strain in Normal, Acutely Ischemic, and Reperfused Myocardium

Jan D’hooge, Oliver Turschner, Christoph Dommke, Piet Claus, more

Lecture Notes in Computer Science > Functional Imaging and Modeling of the Heart > Session 6: Data Acquisition, Experimental, and Modeling Studies > 278-286

Integrated backscatter (IB) and its cyclic variation (CV) are echocardiographic parameters often used for myocardial tissue characterization. Prior work has suggested that IB is directly related to regional scatterer density while its CV could be induced by local myocardial strain. The purpose of this study was to further test this hypothesis by simultaneously recording cyclic changes in IB and myocardial...

article

0118 : Fatty infiltration of the subepicardium of the atrial myocardium is replaced by fibrosis during atrial fibrillation in human and sheep

Peter Haemers, Nadine Suffee, Hadhami Hamdi, Kevin Guedj, more

Archives of Cardiovascular Diseases Supplements > 2016 > 8 > 3 > 228

Accumulation of atrial adipose tissue is associated with atrial fibrillation (AF). However the underlying mechanisms remain poorly understood. We examined the relationship between fatty infiltrations in the atrial myocardium and the development of AF structural/fibrotic substrate.Atrial samples, collected in 92 patients during cardiac surgery and in a sheep model of persistent AF, were subjected to...

article

Anatomical Image Registration Using Volume Conservation to Assess Cardiac Deformation From 3D Ultrasound Recordings

Brecht Heyde, Martino Alessandrini, Jeroen Hermans, Daniel Barbosa, more

IEEE Transactions on Medical Imaging > 2016 > 35 > 2 > 501 - 511

Myocardial deformation imaging can provide valuable insights in myocardial mechanics and help in the diagnosis, prognosis and follow-up of cardiac diseases. However, extracting these indices in 3D is challenging due to the limitations in spatial and temporal resolution of the current volumetric ultrasound systems. For this purpose, we developed an anatomical free-form deformation image registration...

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INFONA - science communication portal

Search results for: Piet Claus

Use of Real‐Time Cine MRI to Assess the Respirophasic Variation of the Inferior Vena Cava—Proof‐of‐Concept and Validation Against Transthoracic Echocardiography

Use of 3D anatomical models in mock circulatory loops for cardiac medical device testing

Altered adrenergic response in myocytes bordering a chronic myocardial infarction underlies in vivo triggered activity and repolarization instability

Area of the pressure-strain loop during ejection as non-invasive index of left ventricular performance: a population study

Inter-vendor reproducibility and accuracy of segmental left ventricular strain measurements using CMR feature tracking

Left ventricular global myocardial strain assessment comparing the reproducibility of four commercially available CMR-feature tracking algorithms

Low-flow support of the chronic pressure–overloaded right ventricle induces reversed remodeling

Atrial volume and function during exercise in health and disease

Left Ventricular Myocardial Segmentation in 3-D Ultrasound Recordings: Effect of Different Endocardial and Epicardial Coupling Strategies

Right ventricular and pulmonary vascular reserve in asymptomatic BMPR2 mutation carriers

A Convolution-based Methodology to Simulate Cardiac Ultrasound Data Sets: Integration of Realistic Beam Profiles

Accuracy of Echocardiography to Evaluate Pulmonary Vascular and RV Function During Exercise

Evaluation of state-of-the-art segmentation algorithms for left ventricle infarct from late Gadolinium enhancement MR images

Why Ischemic Hearts Respond Less to Cardiac Resynchronisation Therapy. A Modeling Study

Left-Ventricular Shape Determines Intramyocardial Stroke Work Distribution

Post-Systolic Thickening in Ischaemic Myocardium: A Simple Mathematical Model for Simulating Regional Deformation

Near horizon supergravity superspace

The Relationship between Regional Integrated Backscatter Levels and Regional Strain in Normal, Acutely Ischemic, and Reperfused Myocardium

0118 : Fatty infiltration of the subepicardium of the atrial myocardium is replaced by fibrosis during atrial fibrillation in human and sheep

Anatomical Image Registration Using Volume Conservation to Assess Cardiac Deformation From 3D Ultrasound Recordings

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