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The preparation and performance of a Ti/IrO2–RuO2–TiO2 anode in the removal of chemical oxygen demand (COD) from biochemically treated landfill leachate by the Fered-Fenton process were investigated. The Taguchi design was applied to obtain the optimal conditions for preparation of the Ti/IrO2–RuO2–TiO2 anode by thermal decomposition method. The optimal preparation conditions were as follows: Ir and...
3-Phosphoinositide-dependent kinase-1 (PDK1) plays a key role in the regulation of physiological processes and its catalytic activity is tightly regulated by allosteric modulators which bind to the PDK1 Interacting Fragment (PIF) pocket. However, details on the allosteric modulators regulation of the PDK1 catalytic activity remain elusive. Here, molecular docking and molecular dynamics (MD) simulations...
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