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In this study, we demonstrate that drug treatments change cardiomyocyte contractile force in vitro. Contractile force was determined by bending deflection of the cantilever end. We quantified the effect of Digoxin, Isoproterenol, and BayK8644, drugs that increase contractile force, on cardiomyocyte contractile forces when grown on the grooved cantilever. We also investigated the effect of Verapamil,...
Cell therapy has been studied a lot to apply to cranial nerve degenerative diseases. But overcoming limitation of low survival rate of transplanted cells is the important thing for cell therapy. For this, studies of transplanting cells in spheroid type are under way. However, the characteristic of cell spheroid is not grasped yet. General MEA can get signals only on a single contact spot with neurospheroid,...
Recently, polymer-based neural probes are being extensively researched because of their potential to reduce neural damage during in vivo and in vitro insertion processes as compared to other types of neural probes. With the progress made in their fabrication processes, polymer probes with various functions, including electrical stimulation, drug delivery, and optical stimulation, are now as much in...
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