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Neonatal administration of diethylstilbestrol (DES) to rodents has adverse effects on spermatogenesis. However, not many studies have been conducted to determine which type of cell – germ or somatic – is the major target of DES. In order to clarify this, we tried reciprocal germ cell transplantation—transplantation of germ cells from DES-treated mice into intact mice and germ cells from normal mice...
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