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Background
Prostate cancer (PC) is the second most lethal cancer for men. For metastatic PC, standard first‐line treatment is androgen deprivation therapy (ADT). While effective, ADT has many metabolic side effects. Previously, we found in serum metabolome analysis that ADT reduced androsterone sulfate, 3‐hydroxybutyric acid, acyl‐carnitines but increased serum glucose. Since ADT reduced ketogenesis,...
OBJECTIVES
To evaluate the longer term changes in executive functioning among participants with cardiovascular disease (CVD) risk factors and cognitive impairments with no dementia (CIND) randomized to a diet and exercise intervention.
DESIGN
A 2 (Exercise) × 2 (Dietary Approaches to Stop Hypertension [DASH] eating plan) factorial randomized clinical trial.
SETTING
Academic tertiary care medical...
Objective
The goal of the present study was to deconstruct the 17 treatment arms used in the Early Adult Reduction of weight through LifestYle (EARLY) weight management trials.
Methods
Intervention materials were coded to reflect behavioral domains and behavior change techniques (BCTs) within those domains planned for each treatment arm. The analytical hierarchy process was employed to determine...
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