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The pursuit of high‐performance batteries has propelled the investigation into advanced materials and design methodologies. Herein, the yolk‐shell MnSe/ZnSe heterojunction encapsulated in hollow carbontubes (MnSe/ZnSe@HCTs) is prepared as a prospective electrode material for sodium/potassium batteries. The band structure in the heterojunction is methodically adjusted and regulated by intentionally...
Neurological diseases are the foremost cause of disability and the second leading cause of death worldwide. Owing to the special microenvironment of neural tissues and biological characteristics of neural cells, a considerable number of neurological disorders are currently incurable. In the past few years, the development of nanoplatforms based on metal–organic frameworks (MOFs) has broadened opportunities...
Pyroptosis is a newly discovered inflammatory form of programmed cell death, which promotes systemic immune response in cancer immunotherapy. GSDMD is one of the key molecules executing pyroptosis, while therapeutical delivery of GSDMD to tumor cells is of great challenge. In this study, an extracellular vesicles‐based GSDMD‐N mRNA delivery system (namely EVTx) is developed for enhanced cancer immunotherapy,...
Engineered Extracellular Vesicles
In article number 2204031, Jing Zhao, Guodong Yang, Angang Yang, and co‐workers develop an extracellular vesicle‐based GSDMD‐N mRNA delivery system (EVTx), in which GSDMD‐N mRNA is encapsulated inside the vesicle, HER2 antibody is displayed on the surface, and sonosensitizer Ce6 is incorporated into the membrane. When endocytosed by HER2+ cancer cells, EVTx efficiently...
Over half of cancer patients are subjected to radiotherapy, but owing to the deficient amount of reactive oxygen radicals (ROS) and DNA double‐strand breaks (DSBs), a fair number of them suffer from radiotherapy resistance and the subsequent short‐term survival opportunity. To overcome it, many successes have been achieved in radiosensitizer discovery using physical strategy and/or biological strategy,...
Polyphosphate (polyP) is one of the most compact inorganic polyanionic biopolymers that participates in various physiological processes. However, the development of polyP‐based nanomaterials is still in its infancy. Here, biocompatible polyphosphate‐manganese nanosheets are designed and synthesized by a hierarchical assembly strategy. The thickness and the lateral size of the resulting polyP‐Mn nanosheets...
As an ion‐embedded material with small strain and low transport energy barrier, the limited ion transport rate and conductivity of niobium pentaoxide (Nb2O5) are the main factors limiting its application in lithium/sodium storage systems. In this work, the microsphere composites (N‐Nb2O5‐x@CNTs) are prepared by combining Nb2O5, rich in nitrogen doping and vacancy defects, with carbon nanotubes (CNTs)...
Even though radiotherapy is the most important therapeutic strategy for colon cancer treatment, there is an enormous demand to improve radiosensitivity in solid tumor destruction. For this purpose, a biomimetic nanoplatform based on hollow polydopamine nanoparticles (HP) with homologous targeting and pH‐responsive drug release properties is designed. In this work, HP is constructed by using a chelation...
Sustainable and cascade anticancer strategies have attracted great attention due to their excellent therapeutic performance. In article number 2000897, Fu‐Gen Wu and co‐workers present a self‐amplified nanoreactor for cancer treatment. The nanoreactor can convert oxygen into HO• for chemodynamic therapy, consume glucose for starvation therapy, and provide a hypoxic environment for hypoxia‐activated...
Fenton reaction‐mediated chemodynamic therapy (CDT) can kill cancer cells via the conversion of H2O2 to highly toxic HO•. However, problems such as insufficient H2O2 levels in the tumor tissue and low Fenton reaction efficiency severely limit the performance of CDT. Here, the prodrug tirapazamine (TPZ)‐loaded human serum albumin (HSA)–glucose oxidase (GOx) mixture is prepared and modified with a metal–polyphenol...
Control of the precise lattice alignment of monolayer molybdenum disulfide (MoS2) on hexagonal boron nitride (h‐BN) is important for both fundamental and applied studies of this heterostructure but remains elusive. The growth of precisely aligned MoS2 domains on the basal plane of h‐BN by a low‐pressure chemical vapor deposition technique is reported. Only relative rotation angles of 0° or 60° between...
Enormous advancement has been achieved in the field of one‐dimensional (1D) semiconductor light‐emitting devices (LEDs), however, LEDs based on 1D CdS nanostructures have been rarely reported. The fabrication of CdS@SiO2 core–shell nanorod array LEDs based on a Au–SiO2–CdS metal–insulator–semiconductor (MIS) structure is presented. The MIS LEDs exhibit strong yellow emission with a low threshold voltage...
MoS2 nanoscrolls are formed by argon plasma treatment on monolayer MoS2 sheet. The nanoscale scroll formation is attributed to the partial removal of top sulfur layer in MoS2 during the argon plasma treatment process. This convenient, solvent‐free, and high‐yielding nanoscroll formation technique is also feasible for other 2D transition metal dichalcogenides.
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