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Serotonin 5-HT 2 receptor availability was evaluated in chronic cocaine abusers (n=19) using positron emission tomography and F-18 N-methylspiperone and was compared to control subjects (n=19). 5-HT 2 Receptor availability was measured in frontal, occipital, cingulate and orbitofrontal cortices using the ratio of the distribution volume in the region of interest to that in the cerebellum...
We assessed the relation between serotonin 5-HT 2 receptor availability and aging and compared it with that for dopamine D 2 receptors on 19 healthy male volunteers (age range, 21-49 years) using positron emission tomography (PET) and F-18 N-methylspiperone (NMS). 5-HT 2 Receptor availability was obtained using the ratio of the distribution volume in the region of interest...
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