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Mitochondrial background has been demonstrated to influence maximal oxygen uptake (VO 2max , in mLkg −1 min −1 ), but this genetic influence can be compensated for by regular exercise. A positive correlation among electron transport chain (ETC) coupling, ATP and reactive oxygen species (ROS) production has been established, and mitochondrial variants have been reported to show...
It has been clearly established that mitochondrial variants, among other potential factors, influence on VO 2max . With this study we sought to determine whether this genetic predisposition could be modified by steady exercise. Mitochondrial genetic variants were determined in 70 healthy controls (CON) and in 77 athletes who trained regularly (50 cyclists, aerobic training (AER), and 27 runners...
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