Search results for: Karim M. Khan

Items from 1 to 20 out of 36 results

article

Action Seniors! Cost‐Effectiveness Analysis of a Secondary Falls Prevention Strategy Among Community‐Dwelling Older Fallers

Jennifer C. Davis, Karim M. Khan, Chun Liang Hsu, Patrick Chan, more

Journal of the American Geriatrics Society > 68 > 9 > 1988 - 1997

BACKGROUND The Otago Exercise Program (OEP) has demonstrated cost‐effectiveness for the primary prevention of falls in a general community setting. The cost‐effectiveness of exercise as a secondary falls prevention (ie, preventing falls among those who have already fallen) strategy remains unknown. The primary objective was to estimate the cost‐effectiveness (incremental cost‐effectiveness/utility...

article

Alignment differs between patellofemoral osteoarthritis cases and matched controls: An upright 3D MRI study

Erin M. Macri, Agnes G. d'Entremont, Kay M. Crossley, Harvi F. Hart, more

Journal of Orthopaedic Research® > 37 > 3 > 640 - 648

Patellofemoral (PF) osteoarthritis (OA) is a prevalent and clinically important knee OA subgroup. Malalignment may be an important risk factor for PF OA. However, little is known about alignment in PF OA, particularly in an upright, weightbearing environment. Using a vertically‐oriented open‐bore MR scanner, we evaluated 3D knee alignment in 15 PF OA cases and 15 individually matched asymptomatic...

article

Patellofemoral and tibiofemoral alignment in a fully weight‐bearing upright MR: Implementation and repeatability

Erin M. Macri, Kay M. Crossley, Agnes G. d'Entremont, Harvi F. Hart, more

Journal of Magnetic Resonance Imaging > 47 > 3 > 841 - 847

Purpose To develop methods for evaluating 3D patellofemoral and tibiofemoral alignment in vertical open‐bore magnetic resonance (MR) scanners, with participants upright and fully weight‐bearing; and to evaluate the repeatability of these methods in individuals with patellofemoral osteoarthritis (OA) and in asymptomatic knees. Materials and Methods Our methods extend previously validated, reliable...

article

Does player unavailability affect football teams’ match physical outputs in the UEFA champions league?

Johann Windt, Jan Ekstrand, Karim M. Khan, Alan McCall, more

Physical Therapy in Sport > 2017 > 28 > C > e24

article

Slow Processing Speed Predicts Falls in Older Adults With a Falls History: 1‐Year Prospective Cohort Study

Jennifer C. Davis, John R. Best, Karim M. Khan, Larry Dian, more

Journal of the American Geriatrics Society > 65 > 5 > 916 - 923

Background/Objectives A previous fall is a strong predictor of future falls. Recent epidemiologic data suggest that deficits in processing speed predict future injurious falls. Our primary objective was to determine a parsimonious predictive model of future falls among older adults who experienced ≥1 fall in the past 12 months based on the following categories: counts of (1) total, (2) indoor, (3)...

article

Lateral displacement, sulcus angle and trochlear angle are associated with early patellofemoral osteoarthritis following anterior cruciate ligament reconstruction

Erin M. Macri, Adam G. Culvenor, Hayden G. Morris, Timothy S. Whitehead, more

Knee Surgery, Sports Traumatology, Arthroscopy > 2018 > 26 > 9 > 2622-2629

Purpose Patellofemoral osteoarthritis (PFOA) occurs in approximately half of anterior cruciate ligament (ACL)-injured knees within 10–15 years of trauma. Risk factors for post-traumatic PFOA are poorly understood. Patellofemoral alignment and trochlear morphology may be associated with PFOA following ACL reconstruction (ACLR), and understanding these relationships, particularly early in the post-surgical...

article

Are the EQ-5D-3L and the ICECAP-O responsive among older adults with impaired mobility? Evidence from the Vancouver Falls Prevention Cohort Study

Jennifer C. Davis, John R. Best, Larry Dian, Karim M. Khan, more

Quality of Life Research > 2017 > 26 > 3 > 737-747

Purpose Preference-based generic measures are gaining increased use in mobility research to assess health-related quality of life and wellbeing. Hence, we examined the responsiveness of these two measures among individuals at risk of mobility impairment among adults aged ≥70 years. Methods We conducted a 12-month prospective cohort study of community-dwelling older adults (n = 288 to n = 341 depending...

chapter

Patellar Tendinopathy: Where Does the Pain Come From?

Jill L. Cook, Karim M. Khan

Anterior Knee Pain and Patellar Instability > Etiopathogenic Bases and Therapeutic Implications > 223-228

The aim of this chapter is to address the question: Where is the pain coming from in patellar tendinopathy? The biochemical sources of pain will be discussed in Patrik Danielson and Alex Scott’s chapter, so this chapter will focus on the potential inflammatory, mechanical, and structural sources in the tendon and surrounding tissues.

chapter

Patellar Tendinopathy and Patellar Tendon Rupture

Karim M. Khan, Jill L. Cook, Nicola Maffulli

Tendon Injuries > Anatomical Sites and Presentation > 166-177

article

Reply

Adam G. Culvenor, Natalie J. Collins, Ali Guermazi, Jill L. Cook, more

Arthritis & Rheumatology > 67 > 9 > 2551 - 2552

article

Early Knee Osteoarthritis Is Evident One Year Following Anterior Cruciate Ligament Reconstruction: A Magnetic Resonance Imaging Evaluation

Adam G. Culvenor, Natalie J. Collins, Ali Guermazi, Jill L. Cook, more

Arthritis & Rheumatology > 67 > 4 > 946 - 955

ObjectiveTo determine the prevalence and factors associated with knee osteoarthritis (OA) defined by magnetic resonance imaging (MRI) and specific OA features on MRI 1 year after anterior cruciate ligament reconstruction (ACLR). MethodsIsotropic 3.0T MRI scans were obtained for 111 participants (71 men; mean ± SD age 30 ± 8 years) 1 year after ACLR as well as for 20 age‐, sex‐, and activity level–matched...

article

Action Seniors! - secondary falls prevention in community-dwelling senior fallers: study protocol for a randomized controlled trial

Teresa Liu-Ambrose, Jennifer C Davis, Chun Liang Hsu, Caitlin Gomez, more

Trials > 2015 > 16 > 1 > 1-9

Background Falls are a ‘geriatric giant’ and are the third leading cause of chronic disability worldwide. About 30% of community-dwellers over the age of 65 experience one or more falls every year leading to significant risk for hospitalization, institutionalization, and even death. As the proportion of older adults increases, falls will place an increasing demand and cost on the health care system...

article

Prevention and Management of Non-Communicable Disease: The IOC Consensus Statement, Lausanne 2013

Gordon O. Matheson, Martin Klügl, Lars Engebretsen, Fredrik Bendiksen, more

Sports Medicine > 2013 > 43 > 11 > 1075-1088

Morbidity and mortality from preventable, non-communicable chronic disease (NCD) threatens the health of our populations and our economies. The accumulation of vast amounts of scientific knowledge has done little to change this. New and innovative thinking is essential to foster new creative approaches that leverage and integrate evidence through the support of big data, technology, and design thinking...

article

Pharmacist‐initiated intervention trial in osteoarthritis: A multidisciplinary intervention for knee osteoarthritis

Carlo A. Marra, Jolanda Cibere, Maja Grubisic, Kelly A. Grindrod, more

Arthritis Care & Research > 64 > 12 > 1837 - 1845

ObjectiveKnee osteoarthritis (OA) is a commonly undiagnosed condition and care is often not provided. Pharmacists are uniquely placed for launching a multidisciplinary intervention for knee OA. MethodsWe performed a cluster randomized controlled trial with pharmacies providing either intervention care or usual care (14 and 18 pharmacies, respectively). The intervention included a validated knee OA...

article

Resistance training and functional plasticity of the aging brain: a 12-month randomized controlled trial

Teresa Liu-Ambrose, Lindsay S. Nagamatsu, Michelle W. Voss, Karim M. Khan, more

Neurobiology of Aging > 2012 > 33 > 8 > 1690-1698

Maintaining functional plasticity of the cortex is essential for healthy aging and aerobic exercise may be an effective behavioral intervention to promote functional plasticity among seniors. Whether resistance training has similar benefits on functional plasticity in seniors has received little investigation. Here we show that 12 months of twice-weekly resistance training led to functional changes...

article

Sport and exercise as contributors to the health of nations

Karim M Khan, Angela M Thompson, Steven N Blair, James F Sallis, more

The Lancet > 2012 > 380 > 9836 > 59-64

Self-reported rates of participation in sport vary by country. In the UK, about 40% of men and women aged 16 years or older participate in at least one sport every week. Although few data exist to assess trends for participation in sport, there is little evidence of change in the past decade among adults. Large cohort studies suggest that such participation in sport is associated with a 20–40% reduction...

article

“She was a little bit unrealistic”: Choice in healthcare decision making for older people

Elisabeth Hicks, Joanie Sims-Gould, Kerry Byrne, Karim M. Khan, more

Journal of Aging Studies > 2012 > 26 > 2 > 140-148

This paper examines autonomy, choice, options, and power in healthcare decision making for older people. Using discourse analysis and a case study from data gathered as part of an ethnographic field study we critique a common conceptualization of healthcare decision making as patients choosing from an array of options offered by healthcare providers. A discourse of “giving options and being realistic”...

article

Corticosteroids: short-term gain for long-term pain?

Alexander Scott, Karim M Khan

The Lancet > 2010 > 376 > 9754 > 1714-1715

article

Mechanotransduction in Human Bone

Alexander Scott, Karim M. Khan, Vincent Duronio, David A. Hart

Sports Medicine > 2008 > 38 > 2 > 139-160

Bone has a remarkable ability to adjust its mass and architecture in response to a wide range of loads, from low-level gravitational forces to high-level impacts. A variety of types and magnitudes of mechanical stimuli have been shown to influence human bone cell metabolism in vitro, including fluid shear, tensile and compressive strain, altered gravity and vibration. Therefore, the current article...

article

Regional trabecular morphology assessed by micro-CT is correlated with failure of aged thoracic vertebrae under a posteroanterior load and may determine the site of fracture

Meena M. Sran, Steven K. Boyd, David M.L. Cooper, Karim M. Khan, more

Bone > 2007 > 40 > 3 > 751-757

Spinal mobilization is commonly used in the treatment of patients with back pain, including individuals with osteoporosis. Previous data indicated that traditional predictors of skeletal failure–lateral or anteroposterior bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA) or geometry of the spinous process or vertebral body–do not predict failure load during posteroanterior spinal...

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INFONA - science communication portal

Search results for: Karim M. Khan

Action Seniors! Cost‐Effectiveness Analysis of a Secondary Falls Prevention Strategy Among Community‐Dwelling Older Fallers

Alignment differs between patellofemoral osteoarthritis cases and matched controls: An upright 3D MRI study

Patellofemoral and tibiofemoral alignment in a fully weight‐bearing upright MR: Implementation and repeatability

Does player unavailability affect football teams’ match physical outputs in the UEFA champions league?

Slow Processing Speed Predicts Falls in Older Adults With a Falls History: 1‐Year Prospective Cohort Study

Lateral displacement, sulcus angle and trochlear angle are associated with early patellofemoral osteoarthritis following anterior cruciate ligament reconstruction

Are the EQ-5D-3L and the ICECAP-O responsive among older adults with impaired mobility? Evidence from the Vancouver Falls Prevention Cohort Study

Patellar Tendinopathy: Where Does the Pain Come From?

Patellar Tendinopathy and Patellar Tendon Rupture

Reply

Early Knee Osteoarthritis Is Evident One Year Following Anterior Cruciate Ligament Reconstruction: A Magnetic Resonance Imaging Evaluation

Action Seniors! - secondary falls prevention in community-dwelling senior fallers: study protocol for a randomized controlled trial

Prevention and Management of Non-Communicable Disease: The IOC Consensus Statement, Lausanne 2013

Pharmacist‐initiated intervention trial in osteoarthritis: A multidisciplinary intervention for knee osteoarthritis

Resistance training and functional plasticity of the aging brain: a 12-month randomized controlled trial

Sport and exercise as contributors to the health of nations

“She was a little bit unrealistic”: Choice in healthcare decision making for older people

Corticosteroids: short-term gain for long-term pain?

Mechanotransduction in Human Bone

Regional trabecular morphology assessed by micro-CT is correlated with failure of aged thoracic vertebrae under a posteroanterior load and may determine the site of fracture

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