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Randomized skin flaps are extensively used in plastic surgery, but the possibility of necrosis has challenged their use. Several studies have been conducted aiming to find ways to reduce the occurrence of necrosis. We evaluated the effects of pentoxifylline (PTX) and hyaluronidase (HLD), each alone or combined, on randomized rat skin flaps.Fifty male Wistar rats were divided into five groups of 10...
Obstructive sleep apnea (OSA) raises the risk of sudden cardiac death (SCD) by 300–400% depending on the severity of OSA. However published reports raised the association between OSA and SCD but not the mechanism of SCD. It is known that OSA exerts profound oxidative stress in the cardiovascular system. Repetitive nocturnal hypoxemia and arousals lead to ischemia reperfusion, cellular degeneration,...
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