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We present a study of the spatial variation of nuclear morphology of stromal and cancer-associated fibroblasts in the mouse mammary gland. The work is part of a framework being developed for the analysis of the tumor microenvironment in breast cancer. Recent research has uncovered the role of stromal cells in promoting tumor growth and progression. In specific, studies have indicated that stromal...
We present an approach for synthesizing biological tissue textures from existing tissue samples. At microscopic resolution, tissues are characterized by a spatial arrangement of nuclei, cytoplasm, red-blood cells (RBCs) and adipose components etc. We employ 2-point correlation functions (2-pcfs) to encode the geometrical aspects of component arrangements in the synthesis process. The 2-pcfs belong...
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